MilliporeSigma
All Photos(1)

Documents

391263

Sigma-Aldrich

2-Dimethylaminoethanol

purified by redistillation, ≥99.5%

Sign Into View Organizational & Contract Pricing

Synonym(s):
N,N-Dimethyl-2-hydroxyethylamine, N,N-Dimethylethanolamine, DMEA, Jeffcat DMEA
Linear Formula:
(CH3)2NCH2CH2OH
CAS Number:
Molecular Weight:
89.14
Beilstein/REAXYS Number:
1209235
EC Number:
MDL number:
PubChem Substance ID:

vapor pressure

100 mmHg ( 55 °C)
6.12 mmHg ( 20 °C)

assay

≥99.5%

form

liquid

purified by

redistillation

refractive index

n20/D 1.4294 (lit.)

bp

134-136 °C (lit.)

mp

−70 °C (lit.)

solubility

alcohol: miscible(lit.)
water: soluble

density

0.886 g/mL at 20 °C (lit.)

SMILES string

CN(C)CCO

InChI

1S/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H3

InChI key

UEEJHVSXFDXPFK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
47145347121640725
vibrant-m

391263

2-Dimethylaminoethanol

vibrant-m

471453

2-Dimethylaminoethanol

vibrant-m

471216

Diethylamine

vibrant-m

40725

1,3-Dimethyl-2-imidazolidinone

solubility

alcohol: miscible(lit.), water: soluble

solubility

H2O: soluble

solubility

water: soluble

solubility

toluene: soluble(lit.), water: miscible

assay

≥99.5%

assay

≥99.5%

assay

≥99.5%

assay

≥99.5% (GC)

mp

−70 °C (lit.)

mp

−70 °C (lit.)

mp

−50 °C (lit.)

mp

-

density

0.886 g/mL at 20 °C (lit.)

density

0.886 g/mL at 20 °C (lit.)

density

0.707 g/mL at 25 °C (lit.)

density

1.056 g/mL at 25 °C (lit.)

bp

134-136 °C (lit.)

bp

134-136 °C (lit.)

bp

55 °C (lit.)

bp

224-226 °C (lit.)

General description

2-Dimethylaminoethanol (DMAE/deanol) is an amino alcohol. It is the main product formed during the amination of ethylene glycol by dimethylamine on alumina supported copper in a continuous fixed-bed reactor. DMAE has been reported to be the putative precursor of acetylcholine. Its effect as a skin-firming and anti-wrinkle agent has been studied. Microwave spectrum of 2-dimethylaminoethanol has been investigated. Its effect as an organic additive on deposition and anti-reflective properties of porous CaF2 has been studied. Removal of the benzyl ester groups by transesterification with 2-dimethylaminoethanol from benzyl protected tripeptides has been reported.

Application

2-Dimethylaminoethanol (deanol) may be used as a ligand in the copper-catalyzed amination of aryl bromides and iodides.
2-Dimethylaminoethanol (deanol, DMAE, DMEA) may be used in the synthesis of the following:
  • cis -[Co(sac)2(dmea)2] and cis -[Zn(sac)2(dmea)2] (sac=saccharinate)
  • heterotrinuclear complex [Cu2Zn(NH3)I3(Me2Ea)3 (HMe2Ea=2-dimethylaminoethanol)
  • 2-alkoxy-N,N-dimethylethylamine
  • mixed-metal complexes of copper(II) and lead(II)

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

104.0 °F - Seta closed cup

flash_point_c

40 °C - Seta closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 6

1 of 6

1-Bromohexadecane 97%

Sigma-Aldrich

234451

1-Bromohexadecane

1-Bromohexane 98%

Sigma-Aldrich

B68240

1-Bromohexane

Ethylbenzene analytical standard

Supelco

03079

Ethylbenzene

1-Bromooctane 99%

Sigma-Aldrich

152951

1-Bromooctane

L E Larsson et al.
International journal of peptide and protein research, 8(1), 39-44 (1976-01-01)
A convenient scheme for the synthesis of 4,8-disubstituted vasopressins has been designed and its usefulness evaluated in the preparation of one of the parent hormones, 8-arginine-vasopressin. The main feature of the scheme involves preparation of two protected tripeptide fragments, Z-Cys(Bzl)-Tyr(Bzl)-Phe
Stimulant effect of 2-dimethylaminoethanol; possible precursor of brain acetylcholine.
C C PFEIFFER et al.
Science (New York, N.Y.), 126(3274), 610-611 (1957-09-27)
Role of organic additives in the sol-gel synthesis of porous CaF2 anti-reflective coatings.
Fujihara S et al
Journal of Sol-Gel Science and Technology, 24(2), 147-154 (2002)
Copper catalyzed amination of ethylene glycol.
Runeberg J, et al.
Applied Catalysis, 17(2), 309-319 (1985)
Copper-catalyzed aryl amination in aqueous media with 2-dimethylaminoethanol ligand.
Lu Z and Twieg RJ.
Tetrahedron Letters, 47(17), 2997-3001 (2005)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service