39391

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide

≥97.0% (T)

• Synonym(s): EDC, WSC, N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide
• Empirical Formula (Hill Notation): C₈H₁₇N₃
• CAS Number: 1892-57-5
• Molecular Weight: 155.24
• Beilstein: 507429
• EC Number: 217-579-2
• MDL number: MFCD00044916
• PubChem Substance ID: 57649895

Properties

• Quality Level: 100
• assay: ≥97.0% (T)
• form: liquid
• reaction suitability: reaction type: Coupling Reactions
• refractive index: n20/D 1.461
• density: 0.877 g/mL at 20 °C (lit.)
• application(s): peptide synthesis
• storage temp.: −20°C
• SMILES string: CCN=C=NCCCN(C)C
• InChI: 1S/C8H17N3/c1-4-9-8-10-6-5-7-11(2)3/h4-7H2,1-3H3
• InChI key: LMDZBCPBFSXMTL-UHFFFAOYSA-N

Description

General description

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide is commonly used in combination with N-hydroxysuccinimide (NHS) in carbodiimide coupling reaction to activate carboxyl group for coupling with amines to form amides.

Application

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide has been used for the surface functionalization of graphene quantum dots (GQDs) employed as sensing probes in Janus micromotors to detect enterobacterial contamination. It has also been used for the activation of folic acid, prior to its conjugation on silica nanoparticles.

Packaging

50 mL in Sure/Seal™

10 mL in glass bottle

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 39391.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety Information

• Pictograms: GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H302 - H311 - H315 - H317 - H373 - H410
• Precautionary Statements: P260 - P273 - P280 - P301 + P312 - P302 + P352 + P312 - P314
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves