394114

Sigma-Aldrich

2-Amino-4-phenylphenol

technical grade, 90%

Linear Formula:
H2NC6H3(C6H5)OH
CAS Number:
Molecular Weight:
185.22
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

grade

technical grade

Quality Level

assay

90%

mp

198-202 °C (lit.)

SMILES string

Nc1cc(ccc1O)-c2ccccc2

InChI

1S/C12H11NO/c13-11-8-10(6-7-12(11)14)9-4-2-1-3-5-9/h1-8,14H,13H2

InChI key

IGIDZGNPFWGICD-UHFFFAOYSA-N

Related Categories

General description

2-Amino-4-phenylphenol is an aminoalcohol derivative. It participates in the synthesis of bisbenzoxazoles.

Application

2-Amino-4-phenylphenol is suitable as an internal standard to investigate the enzymatic activity of N-hydroxy-N-2-fluorenylacetamide (N-OH-2-FAA), a mammary gland carcinogen in the female Sprague-Dawley rat, by HPLC.
It may be used as a chelating agent for metal ions.

Packaging

1 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Synthesis and properties of 4, 4'-bis [5-alkyl (aryl) benzoxazol-2-yl]-2-hydroxy (alkoxy) biphenyls.
Ol'khovik VK, et al.
Russ. J. Org. Chem., 42(8), 1164-1168 (2006)
Metal ion complexing properties of carcinogen metabolites.
J H WEISBURGER et al.
Biochemical pharmacology, 12, 179-191 (1963-02-01)
C L Ritter et al.
Carcinogenesis, 17(11), 2411-2418 (1996-11-01)
N-Hydroxy-N-2-fluorenylacetamide (N-OH-2-FAA) and its benzamide analogue N-OH-2-FBA are mammary gland carcinogens in the female Sprague-Dawley rat. Ovariectomy inhibits tumorigenicity of topically applied N-OH-2-FAA suggesting modulation of carcinogen-activating enzymes in the gland. This study concerned the activation of N-OH-2-FAA and N-OH-2-FBA...

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