402168

6-Bromo-3-formylchromone

99%

• Synonym(s): 6-Bromo-4-oxo-4H-1-benzopyran-3-carboxaldehyde
• Empirical Formula (Hill Notation): C₁₀H₅BrO₃
• CAS Number: 52817-12-6
• Molecular Weight: 253.05
• MDL number: MFCD00191849
• UNSPSC Code: 12352100
• PubChem Substance ID: 24865055
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 99%
• mp: 190-193 °C (lit.)
• functional group: aldehyde; bromo; ketone
• SMILES string: [H]C(=O)C1=COc2ccc(Br)cc2C1=O
• InChI: 1S/C10H5BrO3/c11-7-1-2-9-8(3-7)10(13)6(4-12)5-14-9/h1-5H
• InChI key: PCEZXSJBHMOQFT-UHFFFAOYSA-N
• Gene Information: human ... PTPN1(5770)

Description

General description

6-Bromo-3-formylchromone (6-Bromo-4-oxo-4H-1-benzopyran-3-carboxaldehyde) is a 3-formylchromone derivative. In vivo cytotoxic activity of 6-bromo-3-formylchromone against normal and tumor cells has been tested.[1]

Application

6-Bromo-3-formylchromone is the suitable reagent used in a study to investigate the multidrug resistance reversal by some 3- formylchromones in human colon cancer and mouse lymphoma cells transfected with the human MDR1 gene.[2] It may be used in the preparation of chromone containing sulfonamides.[3]

6-Bromo-3-formylchromone may be used in the preparation of 6′-bromopyranothiazine-4,7-diones.[4]

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves