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MilliporeSigma

409537

Poly(ethylene glycol) methacrylate

average Mn 360, methacrylate, 500-800 ppm MEHQ as inhibitor

Synonym(s):

Ethoxylated 2-hydroxyethyl methacrylate, PEGMA, Poly(ethylene oxide) monomethacrylate, Polyethylene glycol

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100 ML

$89.60

500 ML

$274.00

$89.60


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About This Item

Linear Formula:
H2C=C(CH3)CO(OCH2CH2)nOH
CAS Number:
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:

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Product Name

Poly(ethylene glycol) methacrylate, average Mn 360, contains 500-800 ppm MEHQ as inhibitor

SMILES string

O(CCO)C(=O)C(=C)C

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

InChI key

WOBHKFSMXKNTIM-UHFFFAOYSA-N

form

liquid

mol wt

average Mn 360

contains

500-800 ppm MEHQ as inhibitor

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

refractive index

n20/D 1.464

density

1.105 g/mL at 25 °C

Ω-end

hydroxyl

α-end

methacrylate

polymer architecture

shape: linear
functionality: heterobifunctional

Quality Level

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This Item
447935409529447943
polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: monofunctional

polymer architecture

shape: linear
functionality: heterobifunctional

polymer architecture

shape: linear
functionality: monofunctional

form

liquid

form

-

form

liquid

form

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

mol wt

average Mn 360

mol wt

average Mn 300

mol wt

average Mn 500

mol wt

average Mn 500

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

reaction suitability

reagent type: chemical modification reagent
reaction type: Polymerization Reactions

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

reaction suitability

reagent type: chemical modification reagent
reaction type: Polymerization Reactions

density

1.105 g/mL at 25 °C

density

1.05 g/mL at 25 °C

density

1.101 g/mL at 25 °C

density

1.08 g/mL at 25 °C

General description

Polyethylene glycol (PEG) is a suitable material for biological applications since it does not trigger an immune response. It can by synthesized by anionic ring opening polymerization of ethylene oxide with a range of end groups (such as methacrylate: PEGMA) attached. PEG is a hydrophilic polymer that can form hydrogels when cross linked into networks. Acrylate and methacrylate chain ends undergo chain polymerization to from PEGMA hydrogels.

Application

PEGMA can beused as a monomer to synthesize:
  • Degradable microspheres using asuspension polymerization process. The amphiphilic nature of PEGMA allows performingthe polymerization by direct oil in the water suspension process.
  • Polymeric chelating beads for the effectiveremoval of heavy metals from aqueous solutions.
It can also be used to synthesize micro or nanoparticles-basedchitosan /PEGMA composite by Michael addition reaction. The PEGMA graftingimproves the solubility of chitosan in aqueous media. These particles can beused as carriers in the ophthalmic drug delivery system.

Physical form

Monomethacrylate functionalized

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Certificates of Analysis (COA)

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Biofouling-resistance expanded poly (tetrafluoroethylene) membrane with a hydrogel-like layer of surface-immobilized poly (ethylene glycol) methacrylate for human plasma protein repulsions.
Chang Y, et al.
Journal of Membrane Science, 323(1), 77-84 (2008)
Mir Mukkaram Ali;
Macromolecules, 37, 5219-5227 (2004)

Articles

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Discover hydrogels, biocompatible materials for drug delivery, tissue engineering, wound care, and 3D bioprinting in innovative biomedical applications

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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