417963

Sigma-Aldrich

Chitosan

from shrimp shells, practical grade

Synonym(s):
Deacetylated chitin, Poly(D-glucosamine)
CAS Number:
MDL number:
NACRES:
NA.23

biological source

shrimp shells

Quality Level

grade

practical grade

mol wt

190000-375000 Da

viscosity

>200 cP, 1 wt. % in 1% acetic acid(20 °C, Brookfield)(lit.)

solubility

1 M acetic acid: 10 mg/mL

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

InChI key

FLASNYPZGWUPSU-SICDJOISSA-N

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Related Categories

Application

Forms gels with multivalent anions. Gives clear solutions that dry to strong, clear films.

Packaging

25, 100 g in poly bottle

Features and Benefits

Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.

Physical form

≥ 75% deacetylated

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

nwg

Certificate of Analysis

Certificate of Origin

  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the solubility of Chitosan, Product 417963?

    Product No. 417963 is tested for solubility using 50 mg of chitosan in 5 mL of 1M acetic acid. Solubilization may require heat and sonication. This is a practical grade material, so some insolubles may exist.

  4. What is the molecular weight of the Chitosan, Product 417963, polymer?

    The molecular weight is not measured during quality control and is not guaranteed for this chitosan product. We have an estimated value from the vendor as 190,000->375,000, which is based on the viscosity of 200-2000 mPa.s.

  5. What are some uses for Chitosan, Product 417963?

    Chitosan has recently found many applications in the field of biomaterials. It has been studied for use in biodegradable films, biomedical devices, drug-delivery applications, etc.

  6. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

  9. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Arash Ghalayani Esfahani et al.
Journal of biomedical materials research. Part A, 107(7), 1455-1465 (2019-02-21)
One of the main challenges in the design of scaffolds for cortical bone regeneration is mimicking the highly oriented, hierarchical structure of the native tissue in an efficient, simple, and consistent way. As a possible solution to this challenge, positive...
Liming Hu et al.
Nanoscale, 5(8), 3103-3111 (2013-03-22)
Within the past few years, chitosan-based drug delivery vehicles have become some of the most attractive to be studied. In contrast to all other polysaccharides, chitosan has demonstrated its unique characteristics for drug delivery platforms, including its active primary amino...
Alberto Busilacchi et al.
Carbohydrate polymers, 98(1), 665-676 (2013-08-31)
The idea of using chitosan as a functional delivery aid to support simultaneously PRP, stem cells and growth factors (GF) is associated with the intention to use morphogenic biomaterials to modulate the natural healing sequence in bone and other tissues....
Stephanie Supper et al.
Expert opinion on drug delivery, 11(2), 249-267 (2013-12-07)
Thermogelling chitosan (CS)/glycerophosphate (GP) solutions have been reported as a new type of parenteral in situ forming depot system. These free-flowing solutions at ambient temperature turn into semi-solid hydrogels after parenteral administration. Formulation parameters such as CS physico-chemical characteristics, CS/gelling...
Hajer Aloui et al.
International journal of food microbiology, 170, 21-28 (2013-12-03)
This study reports the efficacy of the combined application of chitosan (CH) and Locust Bean Gum (LBG) in combination with different citrus essential oils (EOs) to inhibit Aspergillus flavus in vitro and on artificially infected dates for a storage period...
Articles
Microparticles with controlled size and morphology are of significant interest in the fields of drug delivery and biopharmaceuticals. The objective of this study was to assess the effect of processing parameters on the ability to control the size and distribution of chitosan based microparticles, targeting diameter range of 1-10 µm. The effect of encapsulating bovine serum albumin (BSA), a model protein, as well as sodium tripolyphosphate (TPP), a cross-linker, was studied.
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Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose.
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The development of new medical devices and pharmaceuticals plays an integral role in the medical industry. Both natural and synthetic polymers possess benefits that make them valuable components in therapeutics.
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Professor Nicola Tirelli (Istituto Italiano di Tecnologia, Italy) highlights the microfluidic-assisted method for fabricating well-defined and reproducible nanoparticles for drug delivery research.
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