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419419

Chitosan

high molecular weight

Synonym(s):

Deacetylated chitin, Poly(D-glucosamine), Chitosan & derivatives

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Pack SizeSKUAvailabilityPrice
50 g
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$114.00
250 g
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$386.00

About This Item

CAS Number:
9012-76-4
UNSPSC Code:
12352201
NACRES:
NA.23
MDL number:
MFCD00161512

$114.00

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Quality Level

100

form

(Coarse ground flakes and powder)

mol wt

310000-375000 Da

viscosity

800-2000 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)

solubility

H2O: insoluble, organic solvents: insoluble

SMILES string

N([C@H]1[C@@H](O[C@@H]([C@H]([C@@H]1O)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4N)O)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5N)O)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6N)O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7N)O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8N)O)O[C@@H]9O[C@@H]([C@H](

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

InChI key

FLASNYPZGWUPSU-SICDJOISSA-N

Application

Forms gels with multivalent anions. Gives clear solutions that dry to strong, clear films.

Features and Benefits

Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.
Biocompatible, antibacterial and environmentally friendly polyelectrolyte.

Physical form

>75% deacetylated

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This Item
448877937657417963
Chitosan high molecular weight

Sigma-Aldrich

419419

Chitosan

Chitosan medium molecular weight

Sigma-Aldrich

448877

Chitosan

Chitosan biomedical research grade, high molecular weight

Sigma-Aldrich

937657

Chitosan

Chitosan from shrimp shells, practical grade

Sigma-Aldrich

417963

Chitosan

solubility

H2O: insoluble, organic solvents: insoluble

solubility

dilute aqueous acid: soluble

solubility

-

solubility

1 M acetic acid: 10 mg/mL

form

(Coarse ground flakes and powder)

form

powder

form

powder or chunks (or Fibers)

form

solid

mol wt

310000-375000 Da

mol wt

-

mol wt

>300 kDa

mol wt

190000-375000 Da

viscosity

800-2000 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)

viscosity

200-800 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)

viscosity

-

viscosity

>200 cP, 1 wt. % in 1% acetic acid(20 °C, Brookfield)(lit.)

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

200

Still not finding the right product?

Explore all of our products under Chitosan

Storage Class

11 - Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCP4147
BCCN4739
BCCL3857
BCCM2871
BCCK6217

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Articles

Electrospinning: Enabling Nanostructured Materials

Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.

Injectable Hydrogels for Tissue Regeneration

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

Tailoring Collagen-Based Matrices for Regenerative Medicine and Tissue Engineering

Collagen molecules play a critical role in tissue architecture and strength, and in cell-matrix interactions as insoluble ligands to regulate the diverse phenotypic activities of cells.

View All Articles

Related Content

Chitosan-based Biomaterials

Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose.

Antonia G Moutzouri et al.
BioMed research international, 2014, 740726-740726 (2014-07-06)
Cell adhesion on substrates is accompanied by significant changes in shape and cytoskeleton organization, which affect subsequent cellular and tissue responses, determining the long-term success of an implant. Alterations in osteoblast stiffness upon adhesion on orthopaedic implants with different surface
Luís Filipe-Ribeiro et al.
Data in brief, 17, 1201-1217 (2018-06-08)
Data in this article presents the changes on phenolic compounds and headspace aroma abundance of a red wine spiked with 4-ethylphenol and 4-ethylguaiacol and treated with a commercial crustacean chitin (CHTN), two commercial crustacean chitosans (CHTB, CHTD), one fungal chitosan
A D Anastasiou et al.
Acta biomaterialia, 71, 86-95 (2018-02-21)
A radical new methodology for the exogenous mineralization of hard tissues is demonstrated in the context of laser-biomaterials interaction. The proposed approach is based on the use of femtosecond pulsed lasers (fs) and Fe3+-doped calcium phosphate minerals (specifically in this
View All Related Papers

Global Trade Item Number

SKUGTIN
419419-50G04061835571550
419419-250G04061832092119

Questions

1–10 of 15 Questions  

  1. What method did you use to prepare chitosan from chitin, and what was the source of the chitin?

    1 answer

    1. According to the M Clarity™ quality program, this product is supplied at the MQ100 level, and therefore, manufacturing process details, including the method used to prepare chitosan from chitin, are considered proprietary. Method and preparation information are only available for products offered at M Clarity™ MQ400 and above. For more information on M Clarity™ quality program please see the link below:
      https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/m-clarity-program

      The source of this chitin product is typically derived from crustaceans or shrimp (Pandalus borealis) shells. This information is available in the lot-specific Certificate of Origin. Please see the link below or navigate to the DOCUMENTATION section of the Product Detail Page to access a Certificate under the ‘Certificate of Origin’ tab: https://www.sigmaaldrich.com/product/aldrich/419419#product-documentation

      Helpful?

  2. What is the minumum purity that applies to all batches? Is the purity measured? How was the molecular weight (even the historical) measured? If it was viscometry could you cite the equations i.e. Mark-Houwink-Sakurada (MHS) and the constants used?

    1 answer

    1. The molecular weight estimate of 310,000-375,000 Da is based upon a rough correlation to the viscosity specification. The molecular weight is not tested on a batch to batch basis.

      Helpful?

  3. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  4. What is the molecular weight?

    1 answer

    1. As indicated in the 'PROPERTIES' section above, the molecular weight of this material may range from 310-375 kDa. The molecular weight of this material is not determined on a lot to lot basis, however historical data indicates the majority of lots will have a range of 340-360 kDa.

      Helpful?

  5. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  6. What is the degree of deacetylation of this group?

    1 answer

    1. The degree of deacetylation is not determined for this product.

      Helpful?

  7. Is it suitable for food-grade use?

    1 answer

    1. This product is not a food grade item, it is intended for research use only. At this time, there is no food grade option available for this material.

      Helpful?

  8. What is the density of this product?

    1 answer

    1. Unfortunately, the density is not determined for this product.

      Helpful?

  9. The source of LMW, MMW and HMW chitosan. most of the LMW and HMW chitosan were products of Iceland and MMW chitosan was a product of USA. Is there a difference in sources of crustaceans used

    1 answer

    1. The source of all chitosan products may vary on a lot-to-lot basis. The source information is typically found on the Certificate of Origin.
      Please see the DOCUMENTATION section of the product detail page and click on the "Certificate of Origin" tab to access a Certificate.

      https://www.sigmaaldrich.com/product/aldrich/419419#product-documentation

      Helpful?

  10. What are some uses for chitosan?

    1 answer

    1. Chitosan is a biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery. Please note that Product No. 419419 is for research purposes only, not for cosmetic or drug use.

      Helpful?

1–10 of 15 Questions  

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