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419508

Sigma-Aldrich

Boron tribromide

ReagentPlus®, ≥99%

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Synonym(s):
Tribromoboron
Empirical Formula (Hill Notation):
BBr3
CAS Number:
Molecular Weight:
250.52
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

vapor density

8.6 (vs air)

Quality Level

vapor pressure

40 mmHg ( 14 °C)

product line

ReagentPlus®

Assay

≥99%

color

colorless to amber

bp

~90 °C (lit.)

mp

−46 °C (lit.)

density

2.60 g/mL at 20 °C (lit.)

SMILES string

BrB(Br)Br

InChI

1S/BBr3/c2-1(3)4

InChI key

ILAHWRKJUDSMFH-UHFFFAOYSA-N

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This Item
230367202207211230
Boron tribromide ReagentPlus®, ≥99%

Sigma-Aldrich

419508

Boron tribromide

Boron tribromide ≥99.99%

Sigma-Aldrich

230367

Boron tribromide

Boron tribromide ReagentPlus®, 99.9%

Sigma-Aldrich

202207

Boron tribromide

bp

~90 °C (lit.)

bp

~90 °C (lit.)

bp

~90 °C (lit.)

bp

-

mp

−46 °C (lit.)

mp

−46 °C (lit.)

mp

−46 °C (lit.)

mp

-

density

2.60 g/mL at 20 °C (lit.)

density

2.60 g/mL at 20 °C (lit.)

density

2.60 g/mL at 20 °C (lit.)

density

0.859 g/mL at 25 °C

vapor density

8.6 (vs air)

vapor density

8.6 (vs air)

vapor density

8.6 (vs air)

vapor density

-

vapor pressure

40 mmHg ( 14 °C)

vapor pressure

40 mmHg ( 14 °C)

vapor pressure

40 mmHg ( 14 °C)

vapor pressure

-

General description

Boron tribromide is a strong Lewis acid generally employed in the deprotection of -OH and -NH groups. It is a moisture-sensitive liquid, which is also used to cleave esters or ethers into alkyl bromides.

Application

Reactant for preparation of:
  • Drug intermediate 6-nitro-L-DOPA
  • Luminescent polystyrene derivatives with sterically protected carbazolylborane moieties
  • High-quality boron-doped graphene via Wurtz-type reductive coupling reaction
  • Mercapto-(+)-methamphetamine haptens for synthesis of (+)-methamphetamine conjugate vaccines with improved epitope densities
  • Micrometer-sized organic molecule-DNA hybrid structures
  • Borane complexes via electrophilic aromatic borylation reactions
  • A 5-HT2C receptor agonist
  • Biphenyl-derivatives possessing tertiary amino groups as β-secretase(BACE1) inhibitors for the treatment of Alzheimer′s disease
  • A highly near-IR region fluorescent p-extended boron aza-dipyrromethene moiety unit
  • Tetrahydroisoquinoline derivatives via intramolecular cyclization of methoxy-substituted N-phenethylimides
Used to cleave aryl methyl ethers in a synthesis of a benzopyranobenzopyran from a coumarin scaffold.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

CorrosionSkull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1A

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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