L-Abrine

Name: <SC>L</SC>-Abrine
Brand: ALDRICH
Price: 691 USD

99%

Synonym(s):

N_α-Methyl-L-tryptophan

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1 G

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About This Item

Empirical Formula (Hill Notation):

C₁₂H₁₄N₂O₂

CAS Number:

526-31-8

Molecular Weight:

218.25

UNSPSC Code:

41116107

NACRES:

NA.22

PubChem Substance ID:

24867181

EC Number:

208-388-5

Beilstein/REAXYS Number:

86638

MDL number:

MFCD00005645

Key Documents

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Product Name

L-Abrine, 99%

InChI key

CZCIKBSVHDNIDH-NSHDSACASA-N

InChI

1S/C12H14N2O2/c1-13-11(12(15)16)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,13-14H,6H2,1H3,(H,15,16)/t11-/m0/s1

SMILES string

CN[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

assay

99%

optical activity

[α]20/D +65°, c = 1 in 0.5 M NaOH

reaction suitability

reaction type: solution phase peptide synthesis

mp

>300 °C (dec.) (lit.)

application(s)

peptide synthesis

Quality Level

100

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Show Differences

1 of 4

This Item	15512	364517	1.08374
Sigma-Aldrich 434248 L-Abrine	Sigma-Aldrich 15512 Boc-Trp-OH	Sigma-Aldrich 364517 L-Tryptophan methyl ester hydrochloride	Millipore 1.08374 L-Tryptophan
assay 99%	assay ≥99.0% (TLC)	assay 98%	assay -
Quality Level 100	Quality Level 200	Quality Level 100	Quality Level 100
mp >300 °C (dec.) (lit.)	mp 136 °C (dec.) (lit.)	mp 218-220 °C (lit.)	mp 290 °C (decomposition)
optical activity [α]20/D +65°, c = 1 in 0.5 M NaOH	optical activity [α]20/D −20±1°, c = 1% in DMF	optical activity [α]20/D +18°, c = 5 in methanol	optical activity -
reaction suitability reaction type: solution phase peptide synthesis	reaction suitability reaction type: Boc solid-phase peptide synthesis	reaction suitability reaction type: solution phase peptide synthesis	reaction suitability -
application(s) peptide synthesis	application(s) peptide synthesis	application(s) peptide synthesis	application(s) -

Biochem/physiol Actions

An indoleamino acid that shows radical scavenging and antioxidant properties in vitro.

pictograms

GHS07

signalword

Warning

hcodes

H302 + H312 + H332

pcodes

P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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GARP is regulated by miRNAs and controls latent TGF-β1 production by human regulatory T cells.

Emilie Gauthy et al.

PloS one, 8(9), e76186-e76186 (2013-10-08)

GARP is a transmembrane protein present on stimulated human regulatory T lymphocytes (Tregs), but not on other T lymphocytes (Th cells). It presents the latent form of TGF-β1 on the Treg surface. We report here that GARP favors the cleavage

Critical review of heavy metal pollution of traffic area runoff: Occurrence, influencing factors, and partitioning.

Maximilian Huber et al.

The Science of the total environment, 541, 895-919 (2015-10-09)

A dataset of 294 monitored sites from six continents (Africa, Asia, Australia, Europe, North and South America) was compiled and evaluated to characterize the occurrence and fate of heavy metals in eight traffic area categories (parking lots, bridges, and three

Substrate promiscuity of the cyclic dipeptide prenyltransferases from Aspergillus fumigatus ( section sign).

Huixi Zou et al.

Journal of natural products, 72(1), 44-52 (2008-12-31)

This study reports that a series of tryptophan derivatives with modifications on the side chain or at the indole ring were accepted by two cyclic dipeptide prenyltransferases, CdpNPT and FtmPT1, and converted to prenylated derivatives. The structures of the enzymatic

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