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Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)

average Mn ~2,900

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Synonym(s):
Pluronic® L-64, PEG-PPG-PEG
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

vapor density

>1 (vs air)

Quality Level

vapor pressure

<0.3 mmHg ( 20 °C)

form

viscous liquid

mol wt

average Mn ~2,900

composition

PEG, 40 wt. %

refractive index

n20/D 1.46

surface tension

43 dyn/cm, 25 °C, 0.1 wt. % in H2O

viscosity

850 cP(25 °C, Brookfield)(lit.)

transition temp

cloud point 58 °C (1 wt. % aqueous solution)

density

1.05 g/mL at 25 °C

HLB

12.0 - 18.0

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

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1 of 4

This Item
4123254354651546106
Poloxalene United States Pharmacopeia (USP) Reference Standard

1546106

Poloxalene

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

-

viscosity

850 cP(25 °C, Brookfield)(lit.)

viscosity

1,000 cP(77 °C, Brookfield)(lit.)

viscosity

350 cP(60 °C, Brookfield)(lit.)

viscosity

-

transition temp

cloud point 58 °C (1 wt. % aqueous solution)

transition temp

cloud point >100 °C (1 wt. % aqueous solution), Tm 52 °C

transition temp

Tm (DSC) 39 °C (at peak), cloud point 90 °C (1 wt. % aqueous solution)

transition temp

-

density

1.05 g/mL at 25 °C

density

1.06 g/mL at 25 °C

density

1.018 g/mL at 25 °C

density

-

mol wt

average Mn ~2,900

mol wt

average Mn ~8,400

mol wt

average Mn ~5,800

mol wt

Mw ~3000

Application

Hard and soft surface cleaners, defoamers in coatings and water treatment. Lubricant in metal working, anti-foaming aid and extender for linear and cross-linked polyesters and polyurethanes.

Features and Benefits

Surface active material whose properties are dependent on the hydrophilic (EO)/hydrophobic (PO) ratio. High EO content gives better o/w stabilizers.

Physical form

Terminal primary dihydroxy-functional oligomer.

Legal Information

Pluronic is a registered trademark of BASF

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Colloids and surfaces. B, Biointerfaces, 99, 27-37 (2011-10-18)
Polyplex particles formed with plasmid DNA (pDNA) and Pluronic P85-block-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} (P85-b-P[Asp(DET)]) demonstrated highly effective transfection ability compared to PEG-based block cationomer, PEG-b-P[Asp(DET)]. Ternary polyplexes comprising PEG-b-P[Asp(DET)], poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)-b-P[Asp(DET)] (P(EPE)-b-P[Asp(DET)]) used as an analog of P85-b-P[Asp(DET)], and pDNA were
Xijun Zhang et al.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 31(6), 842-845 (2011-12-17)
This study examined the effect of P85 (a pluronic block copolymer) and microbubble (MB) ultrasound contrast agents under ultrasound irradiation on gene transfection and expression. The pEGFP plasmids that can encode enhanced green fluorescent protein (pEGFP) served as a report
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The Time Trade-Off (TTO) is an instrument used for valuing health-related quality of life. This study evaluated the test-retest reliability of a computer TTO in rheumatoid arthritis (RA), and compared the computer with the interview TTO regarding feasibility and agreement.
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The block polyethers PEO-PPO-ph-PPO-PEO (BPE) and PPO-PEO-ph-PEO-PPO (BEP) are synthesized by anionic polymerization using bisphenol A as initiator. Compared with Pluronic P123, the aggregation behaviors of BPE and BEP at an air/water interface are investigated by the surface tension and
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Drug resistance is a main obstacle for the successful chemotherapy of lung cancer. In this work, a new co-delivery system, P85-PEI/TPGS/PTX/shSur complex nanoparticles (PTPNs), to overcome paclitaxel (PTX) resistance in A549 human lung cancer was designed and developed. The experimental

Articles

Mesoporous materials are formed by a self-assembly process from combined solutions of sol-gel precursors (e.g., metal alkoxides) and structure-directing amphiphiles, usually block-copolymers or surfactants.

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