441902

Cesium carbonate

ReagentPlus^®, 99%

• Synonym(s): Carbonic acid dicesium
• Linear Formula: Cs₂CO₃
• CAS Number: 534-17-8
• Molecular Weight: 325.82
• Beilstein: 4546405
• EC Number: 208-591-9
• MDL number: MFCD00010957
• PubChem Substance ID: 24867711
• NACRES: NA.22

Properties

• Quality Level: 200
• product line: ReagentPlus^®
• Assay: 99%
• form: powder and chunks
• mp: 610 °C (dec.) (lit.)
• SMILES string: [Cs+].[Cs+].[O-]C([O-])=O
• InChI: 1S/CH2O3.2Cs/c2-1(3)4;;/h(H2,2,3,4);;/q;2*+1/p-2
• InChI key: FJDQFPXHSGXQBY-UHFFFAOYSA-L

Description

General description

Cesium carbonate is a powerful inorganic base widely used in organic synthesis. It is a potential chemoselective catalyst for the reduction of aldehydes and ketones to alcohols. It is employed as base for the Heck coupling reaction of 4-trifluoromethyl-1-chlorobenzene and aryl chlorides.

Application

Cesium carbonate can be used as a base in C-C and C-N cross-coupling reactions such as Suzuki−Miyaura, Heck, and Buchwald-Hartwig amination reactions. It is also used as a base in alkylation reactions.

Promotes the efficient O-alkylation of alcohols to form mixed alkyl carbonates.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Safety Information

• Pictograms: GHS05,GHS08
• Signal Word: Danger
• Hazard Statements: H318 - H361f - H373
• Precautionary Statements: P202 - P260 - P280 - P305 + P351 + P338 - P308 + P313 - P405
• Hazard Classifications: Eye Dam. 1 - Repr. 2 - STOT RE 2 Oral
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves