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448877

Sigma-Aldrich

Chitosan

medium molecular weight

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Synonym(s):
Deacetylated chitin, Poly(D-glucosamine)
CAS Number:
MDL number:
NACRES:
NA.23

Quality Level

form

powder

viscosity

200-800 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)

solubility

dilute aqueous acid: soluble

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

Inchi Key

FLASNYPZGWUPSU-SICDJOISSA-N

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This Item
417963448869419419
Chitosan medium molecular weight

Sigma-Aldrich

448877

Chitosan

Chitosan from shrimp shells, practical grade

Sigma-Aldrich

417963

Chitosan

Chitosan low molecular weight

Sigma-Aldrich

448869

Chitosan

Chitosan high molecular weight

Sigma-Aldrich

419419

Chitosan

solubility

dilute aqueous acid: soluble

solubility

1 M acetic acid: 10 mg/mL

solubility

dilute aqueous acid: soluble

solubility

H2O: insoluble, organic solvents: insoluble

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

viscosity

200-800 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)

viscosity

>200 cP, 1 wt. % in 1% acetic acid(20 °C, Brookfield)(lit.)

viscosity

20-300 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)

viscosity

800-2000 cP, 1 wt. % in 1% acetic acid(25 °C, Brookfield)(lit.)

Application

Chitosan may be used as a flocculant, in protein precipitation, encapsulating agent and aqueous thickener.
Forms gels with multivalent anions. Gives clear solutions that dry to strong, clear films.

Features and Benefits

Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.

Physical form

75-85% deacetylated

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Mohammad Amin Shamekhi et al.
International journal of biological macromolecules, 127, 396-405 (2019-01-10)
Enhancement of physical and mechanical properties of the scaffolds is achieved via various methods including cross-linking and incorporation of nano particles. In the present research chitosan-based scaffolds firstly were reinforced with the incorporation of the graphene oxide (GO) nanoparticles. The
Arnout Mieremet et al.
PloS one, 12(3), e0174478-e0174478 (2017-03-24)
Full thickness human skin models (FTMs) contain an epidermal and a dermal equivalent. The latter is composed of a collagen dermal matrix which harbours fibroblasts. Current epidermal barrier properties of FTMs do not fully resemble that of native human skin
Viviana Vergaro et al.
International journal of biological macromolecules, 99, 187-195 (2017-02-25)
Carbohydrate polimeric microcapsules were assembled using a LbL approach onto a CaCO
Paulo V O Toledo et al.
International journal of biological macromolecules, 123, 1180-1188 (2018-11-24)
Xanthan gum (XG) was applied for the creation of hydrophilic, hydrophobic and layered cryogels. Firstly, the correlation among synthesis parameters, such as solvent composition and polymer concentration (Cp) in the precursor gel and mold diameter (Φ), with physicochemical properties and
Lana Glerieide Silva Garcia et al.
Carbohydrate polymers, 195, 662-669 (2018-05-29)
Difficulties in the treatment of Candida spp. invasive infections are usually related to the formation of biofilms. The aim of this study was to determine the effects of molecular weight (MW) of chitosan (using high (HMW), medium (MMW) and low

Articles

Chitosan: A Versatile Platform for Pharmaceutical Applications

The development of new medical devices and pharmaceuticals plays an integral role in the medical industry. Both natural and synthetic polymers possess benefits that make them valuable components in therapeutics.

Preparation of Chitosan Microparticles by Spray Drying

Microparticles with controlled size and morphology are of significant interest in the fields of drug delivery and biopharmaceuticals. The objective of this study was to assess the effect of processing parameters on the ability to control the size and distribution of chitosan based microparticles, targeting diameter range of 1-10 µm. The effect of encapsulating bovine serum albumin (BSA), a model protein, as well as sodium tripolyphosphate (TPP), a cross-linker, was studied.

Chitosan-based Biomaterials

Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose.

Chitosan Biopolymer from Fungal Fermentation for Delivery of Chemotherapeutic Agents

Chitosan is a naturally occurring polysaccharide ideally suited for use in medical supplies, devices, therapeutics, and diagnostics. The unique natural characteristics of chitosan include its cationic, biocompatible, biodegradable, non-toxic, non-immunogenic, and antimicrobial properties.

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