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457620

Sigma-Aldrich

Polyglycolide

inherent viscosity 1.4dL/g

Synonym(s):
PGA, Poly(glycolic acid)
Linear Formula:
(C2H4O3)n
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

Quality Level

form

solid

degradation timeframe

6-12 months

inherent viscosity

1.1-1.7 dL/g, 0.1 % (w/v) in hexafluoroisopropanol(25 °C)

transition temp

Tm 220-230 °C

solubility

hexafluoroisopropanol: soluble

density

1.53 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

OCC(O)=O

InChI

1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)

InChI key

AEMRFAOFKBGASW-UHFFFAOYSA-N

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General description

Biodegradable and biocompatible PGA could be potentially useful for bone regeneration. High molecular weight polyglycolide (PGA) can be prepared by ring opening polymerization of diglycolide in the presence of diphenyl bismuth bromide.

Application

Polyglycolide (PGA) along with polylactide may be used to prepare a biodegradable copolymer to be used as implantations. Fabrication of biopolymer/carbon nanotube composite has been reported using PGA fiber as one of the constituents of the composite. Modified porous PGA scaffolds has been fabricated.
medical device

Packaging

1, 5, 10 g in glass bottle

Physical properties

Biodegradable polymer

Preparation Note

To achieve solubility in hexafluoroisopropanol, melt crystalline product and quench with liquid nitrogen to change material to amorphous form.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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