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Boc-Cys(Trt)-OH

Name: Boc-Cys(Trt)-OH
Brand: ALDRICH
Price: 61.2 USD

97%, for peptide synthesis

Synonym(s):

N-(tert-Butoxycarbonyl)-S-trityl-L-cysteine, N_α-Boc-S-trityl-L-cysteine

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Pack Size	SKU	Availability	Price
5 g		Check Cart for Availability	$81.60 $61.20
25 g		Check Cart for Availability	$336.00

About This Item

Linear Formula:

(C₆H₅)₃CSCH₂CH[NHCO₂C(CH₃)₃]CO₂H

CAS Number:

21947-98-8

Molecular Weight:

463.59

NACRES:

NA.22

PubChem Substance ID:

24869538

UNSPSC Code:

12352209

EC Number:

244-674-6

MDL number:

MFCD00038251

Beilstein/REAXYS Number:

2028965

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Properties

Product Name

Boc-Cys(Trt)-OH, 97%

Quality Level

200

assay

97%

optical activity

[α]20/D +27.5°, c = 1 in ethanol

reaction suitability

reaction type: Boc solid-phase peptide synthesis

mp

143-146 °C (lit.)

application(s)

peptide synthesis

SMILES string

CC(C)(C)OC(=O)N[C@@H](CSC(c1ccccc1)(c2ccccc2)c3ccccc3)C(O)=O

InChI

1S/C27H29NO4S/c1-26(2,3)32-25(31)28-23(24(29)30)19-33-27(20-13-7-4-8-14-20,21-15-9-5-10-16-21)22-17-11-6-12-18-22/h4-18,23H,19H2,1-3H3,(H,28,31)(H,29,30)/t23-/m0/s1

InChI key

JDTOWOURWBDELG-QHCPKHFHSA-N

Description

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This Item	15375	164739	08503
Sigma-Aldrich 459313 Boc-Cys(Trt)-OH	Sigma-Aldrich 15375 Boc-Cys(StBu)-OH	Sigma-Aldrich 164739 (+)-S-Trityl-L-cysteine	Sigma-Aldrich 08503 Fmoc-D-Cys(Trt)-OH
assay 97%	assay ≥99.0% (TLC)	assay 97%	assay ≥97.0% (HPLC)
optical activity [α]20/D +27.5°, c = 1 in ethanol	optical activity [α]20/D −153±3°, c = 2% in methanol	optical activity [α]25/D +115°, c = 0.8 in 0.04 M ethanolic HCl	optical activity -
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 100
mp 143-146 °C (lit.)	mp 117-119 °C	mp 182-183 °C (dec.) (lit.)	mp -
application(s) peptide synthesis	application(s) peptide synthesis	application(s) peptide synthesis	application(s) peptide synthesis
reaction suitability reaction type: Boc solid-phase peptide synthesis	reaction suitability reaction type: Boc solid-phase peptide synthesis	reaction suitability reaction type: solution phase peptide synthesis	reaction suitability reaction type: Fmoc solid-phase peptide synthesis

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Making Ends Meet: Microwave-Accelerated Synthesis of Cyclic and Disulfide Rich Proteins Via In Situ Thioesterification and Native Chemical Ligation.

Sunithi Gunasekera et al.

International journal of peptide research and therapeutics, 19(1), 43-54 (2013-03-19)

The development of synthetic methodologies for cyclic peptides is driven by the discovery of cyclic peptide drug scaffolds such as the plant-derived cyclotides, sunflower trypsin inhibitor 1 (SFTI-1) and the development of cyclized conotoxins. Currently, the native chemical ligation reaction

Self-Immolative Fluorescent and Raman Probe for Real-Time Imaging and Quantification of γ-Glutamyl Transpeptidase in Living Cells.

Yang Zhang et al.

ACS applied materials & interfaces, 11(31), 27529-27535 (2019-07-11)

Characterizing over-expressed enzymes or biomarkers in living cells is critical for the molecular understanding of disease pathology and consequently for designing precision medicines. Herein, a "switch-on" probe is designed to selectively detect γ-glutamyl transpeptidase (GGT) in living cells via a

Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors.

Naohisa Ogo et al.

Bioorganic & medicinal chemistry letters, 17(14), 3921-3924 (2007-05-26)

Inhibition of Eg5 represents a novel approach for the treatment of cancer. Here, we report the synthesis and structure-activity relationship of S-trityl-L-cysteine (STLC) derivatives as Eg5 inhibitors. Some of these derivatives such as 4f demonstrated enhanced inhibitory activity against Eg5

Global Trade Item Number

SKU	GTIN
459313-5G	04061833466452
459313-25G	04061833482797

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Boc-Cys(Trt)-OH

97%, for peptide synthesis

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About This Item

$61.20

Product Name

Quality Level

assay

optical activity

reaction suitability

mp

application(s)

SMILES string

InChI

InChI key

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This Item

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ppe

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Boc-Cys(Trt)-OH

97%, for peptide synthesis

Select a Size

About This Item

459313-5G

$61.20

Product Name

Quality Level

assay

optical activity

reaction suitability

mp

application(s)

SMILES string

InChI

InChI key

Compare Similar Items

This Item

Still not finding the right product?

Safety Information

Storage Class

wgk

flash_point_f

flash_point_c

ppe

Documentation

Certificates of Analysis (COA)

Already Own This Product?

Peer Reviewed Papers

Global Trade Item Number

Questions

Reviews

Active Filters