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461350

Sigma-Aldrich

1-Boc-4-piperidone

98%

Synonym(s):

N-Boc-4-piperidone, tert-Butyl 4-oxo-1-piperidinecarboxylate

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5 G
$55.80
25 G
$190.00
100 G
$553.00

About This Item

Empirical Formula (Hill Notation):
C10H17NO3
CAS Number:
Molecular Weight:
199.25
Beilstein/REAXYS Number:
3650236
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

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Quality Level

assay

98%

mp

73-77 °C (lit.)

functional group

ketone

SMILES string

CC(C)(C)OC(=O)N1CCC(=O)CC1

InChI

1S/C10H17NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h4-7H2,1-3H3

InChI key

ROUYFJUVMYHXFJ-UHFFFAOYSA-N

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1 of 4

This Item
495484640042641472
assay

98%

assay

97%

assay

97%

assay

97%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

mp

73-77 °C (lit.)

mp

61-65 °C (lit.)

mp

-

mp

-

functional group

ketone

functional group

hydroxyl

functional group

-

functional group

amine

General description

1-Boc-4-piperidone is used as a precursor in the synthesis of synthetic drugs and as a building block for the preparation of selective ligands. [1][2]

Application

1-Boc-4-piperidone, a pharma building block,[3][4][5][6] may be used in the synthesis of (3E,5E)-3,5-bis(2,5-dimethoxybenzylidene)-1-t-butoxycarbonylpiperidin-4-one (RL197).[7] It may also be used in the synthesis of spirorifamycins containing a piperidine ring structure.[8]

Warning

Avoid metal contact.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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