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465119
Baicalein
98%
All Photos(1)
Synonym(s):
5,6,7-Trihydroxyflavone
Empirical Formula (Hill Notation):
C15H10O5
CAS Number:
Molecular Weight:
270.24
Beilstein/REAXYS Number:
272683
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Quality Level
assay
98%
mp
256-271 °C (lit.)
SMILES string
Oc1cc2OC(=CC(=O)c2c(O)c1O)c3ccccc3
InChI
1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H
InChI key
FXNFHKRTJBSTCS-UHFFFAOYSA-N
Gene Information
mouse ... Hexa(15211)
rat ... Alox15(81639) , Alox5(25290)
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General description
Baicalein, a flavonoid, is a xanthine oxidase inhibitor. Anti-inflammatory effects of baicalein in peripheral human leukocytes has been studied.
Application
Baicalein was used in a study to investigate the in vitro quantitative inhibition of lipoxygenase.
Packaging
100, 500 mg in amber glass bottle
Biochem/physiol Actions
The flavonoid component of Nepalese and Sino-Japanese crude drugs. Baicalein, a major flavone of Scutellariae baicalensis, inhibits the 12-lipoxygenase (12-LOX) pathway of arachidonic acid metabolism, which inhibits cancer cell proliferation and induces apoptosis.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 465119.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Personal Protective Equipment
RIDADR
NONH for all modes of transport
WGK Germany
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificate of Analysis
Certificate of Origin
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