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469963

Sigma-Aldrich

L-Threoninol

97%

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Synonym(s):
(2R,3R)-2-Amino-1,3-butanediol
Linear Formula:
CH3CH(OH)CH(NH2)CH2OH
CAS Number:
Molecular Weight:
105.14
Beilstein/REAXYS Number:
6130524
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

97%

form

solid

optical activity

[α]20/D −4.2°, c = 1% in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

49-54 °C (lit.)

application(s)

peptide synthesis

SMILES string

C[C@@H](O)[C@H](N)CO

InChI

1S/C4H11NO2/c1-3(7)4(5)2-6/h3-4,6-7H,2,5H2,1H3/t3-,4-/m1/s1

InChI key

MUVQIIBPDFTEKM-QWWZWVQMSA-N

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1 of 4

This Item
605034I7634237639
L-Threoninol 97%

469963

L-Threoninol

L-Threonine-1-13C 99 atom % 13C, 97% (CP)

605034

L-Threonine-1-13C

D-Isoleucine ≥98% (TLC)

I7634

D-Isoleucine

(2R,3R)-(−)-2,3-Butanediol 97%

237639

(2R,3R)-(−)-2,3-Butanediol

assay

97%

assay

97% (CP)

assay

≥98% (TLC)

assay

97%

mp

49-54 °C (lit.)

mp

256 °C (dec.) (lit.)

mp

-

mp

-

optical activity

[α]20/D −4.2°, c = 1% in H2O

optical activity

-

optical activity

-

optical activity

[α]23/D −13.2°, neat

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

-

reaction suitability

reaction type: solution phase peptide synthesis

reaction suitability

-

reaction suitability

-

reaction suitability

-

General description

L-Threoninol also known as (2R,3R)-2-Amino-1,3-butanediol, is an amino alcohol, which is commonly used in solution phase peptide synthesis.

Application

L-Threoninol can be used as artificial abasic nucleoside in the synthesis and modification of oligodeoxynucleotide and can also be utilized to synthesize pyrene-L-threoninyl analogues.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Synthesis and properties of an oligonucleotide modified with an acridine derivative at the artificial abasic site
K Fukui
Bioconjugate Chemistry, 7, 349-355 (1996)
Potent triple helix stabilization by 5?, 3?-modified triplex-forming oligonucleotides
N Ben Gaied
Chembiochem, 10, 1839-1851 (2009)

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