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MilliporeSigma

471453

2-Dimethylaminoethanol

≥99.5%

Synonym(s):

N,N-Dimethyl-2-hydroxyethylamine, N,N-Dimethylethanolamine, Jeffcat DMEA

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100 ML

$33.80

500 ML

$46.70

2 L

$129.00

18 L

$629.00

$33.80


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About This Item

Linear Formula:
(CH3)2NCH2CH2OH
CAS Number:
Molecular Weight:
89.14
Beilstein/REAXYS Number:
1209235
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

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vapor pressure

100 mmHg ( 55 °C)
6.12 mmHg ( 20 °C)

Quality Level

assay

≥99.5%

refractive index

n20/D 1.4294 (lit.)

bp

134-136 °C (lit.)

mp

−70 °C (lit.)

solubility

H2O: soluble

density

0.886 g/mL at 20 °C (lit.)

functional group

amine
hydroxyl

SMILES string

CN(C)CCO

InChI

1S/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H3

InChI key

UEEJHVSXFDXPFK-UHFFFAOYSA-N

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1 of 4

This Item
3899039126350632
assay

≥99.5%

assay

≥98.0% (GC)

assay

≥99.5%

assay

≥99.0% (GC)

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

solubility

H2O: soluble

solubility

H2O: soluble

solubility

alcohol: miscible(lit.), water: soluble

solubility

H2O: soluble

refractive index

n20/D 1.4294 (lit.)

refractive index

n20/D 1.4294 (lit.), n20/D 1.430

refractive index

n20/D 1.4294 (lit.)

refractive index

n20/D 1.4294 (lit.)

bp

134-136 °C (lit.)

bp

134-136 °C (lit.)

bp

134-136 °C (lit.)

bp

134-136 °C (lit.)

mp

−70 °C (lit.)

mp

−70 °C (lit.)

mp

−70 °C (lit.)

mp

−70 °C (lit.)

General description

2-Dimethylaminoethanol (deanol, DMAE) is a precursor of acetylcholine.[1][2] Microwave spectral studies on DMAE have reported the following values; the rotational constants (MHz) A = 5814.0(2), B = 2214.54(2), and C = 2037.96(2) and a dipole moment of 2.56 D, with a, b, and c components (D) of 2.27(2), 0.3(1), and 1.16(5), respectively.[3]

Application

2-Dimethylaminoethanol (deanol, DMAE) may be employed as a ligand in the copper-catalyzed amination of aryl bromides and iodides.[4]

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

104.0 °F - Seta closed cup

flash_point_c

40 °C - Seta closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Occurrence and quantitative determination of 2-dimethylaminoethanol in animal tissue extracts.
C G HONEGGER et al.
Nature, 184(Suppl 8), 550-552 (1959-08-15)
Copper-catalyzed aryl amination in aqueous media with 2-dimethylaminoethanol ligand.
Lu Z and Twieg RJ.
Tetrahedron Letters, 46(17), 2997-3001 (2005)
Split face study on the cutaneous tensile effect of 2-dimethylaminoethanol (deanol) gel.
Uhoda I, et al.
Skin Research and Technology, 8(3), 164-167 (2002)
Microwave spectrum and hydrogen bonding in 2-dimethylaminoethanol.
Penn RE and Birkenmeier JA
Journal of Molecular Spectroscopy, 62(3), 416-422 (1976)
Tadashi Tatsumi et al.
Bioorganic & medicinal chemistry, 18(7), 2720-2727 (2010-03-17)
Effects of retro-inverso (RI) modifications of HTLV-1 protease inhibitors containing a hydroxyethylamine isoster backbone were clarified. Construction of the isoster backbone was achieved by a stereoselective aldol reaction. Four diastereomers with different configurations at the isoster hydroxyl site and the

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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