475254

Sigma-Aldrich

2-Amino-6-bromopurine

95%

Empirical Formula (Hill Notation):
C5H4BrN5
CAS Number:
Molecular Weight:
214.02
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

95%

mp

>350 °C (lit.)

SMILES string

Nc1nc(Br)c2nc[nH]c2n1

InChI

1S/C5H4BrN5/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H3,7,8,9,10,11)

InChI key

HPGBGNVPUMCKPM-UHFFFAOYSA-N

General description

2-Amino-6-bromopurine is a 2-amino-6-halogenopurine. It can be synthesized by reaction between 2-amino-6-chloropurine and KX (X=Br). It has been reported to be a substrate for the adenine deaminase. Orientations of 2-amino-6-bromopurine (ABPu) in the docking conformations of guanine riboswitch complexed with ABPu have been analyzed.

Packaging

1, 5 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Codes

Xn

Risk Statement

22

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Synthesis of Some Biologically Active Halogenopurines.
Hu YL, et al.
J. Korean Chem. Soc., 54(4), 429-436 (2010)
Theoretical studies on the interaction of guanine riboswitch with guanine and its closest analogues.
Ling B, et al.
Molecular Simulations, 36(12), 929-938 (2010)
D A Jankowska et al.
Journal of applied microbiology, 115(5), 1134-1146 (2013-08-02)
Construction of a transgenic Arxula adeninivorans strain that produces a high concentration of adenine deaminase and investigation into the application of the enzyme in the production of food with low purine content. The A. adeninivorans AADA gene, encoding adenine deaminase...

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