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Poly(ethylene glycol) diglycidyl ether

average Mn 500

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Synonym(s):
Diepoxy PEG, PEG diglycidyl ether, Polyoxyethylene bis(glycidyl ether)
Linear Formula:
C3H5O2-(C2H4O)n-C3H5O
CAS Number:
NACRES:
NA.23

mol wt

average Mn 500

Quality Level

reaction suitability

reagent type: cross-linking reagent
reactivity: amine reactive

refractive index

n20/D 1.47

Ω-end

glycidyl

α-end

glycidyl

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

2-8°C

InChI

1S/C8H14O4/c1(9-3-7-5-11-7)2-10-4-8-6-12-8/h7-8H,1-6H2

InChI key

AOBIOSPNXBMOAT-UHFFFAOYSA-N

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1 of 4

This Item
455008731811731803
Poly(ethylene glycol) diacrylate average Mn 700

455008

Poly(ethylene glycol) diacrylate

mol wt

average Mn 500

mol wt

average Mn 700

mol wt

average Mn 2,000

mol wt

Mn 6,000

reaction suitability

reagent type: cross-linking reagent
reactivity: amine reactive

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

reaction suitability

reagent type: cross-linking reagent
reactivity: amine reactive

reaction suitability

reagent type: cross-linking reagent
reactivity: amine reactive

α-end

glycidyl

α-end

acrylate

α-end

-

α-end

-

Ω-end

glycidyl

Ω-end

acrylate

Ω-end

-

Ω-end

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

General description

Poly(ethylene glycol) diglycidyl ether (PEGDGE) shows highly solubility in water. Hence, it easily undergoes hydrolysis followed by ring cleavage reaction in aqueous solution, yielding hydroxyl group. PEGDGE combines with proteins covalently or non-covalently. PEGDGE is widely used in chemical industries for cross linking and surface modifier.

Application

The high solubility of PEGDGE has been successfully employed to immobilize glucose oxidase, d-amino acid oxidase and glutamate oxidase. It may be used as a component for the development of microelectrode biosensors to detect hydrogen peroxide and nitric oxide.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

386.6 °F - closed cup

flash_point_c

197.00 °C - closed cup

ppe

Eyeshields, Gloves


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Direct electrochemistry and electrocatalysis of hemoglobin on a glassy carbon electrode modified with poly (ethylene glycol diglycidyl ether) and gold nanoparticles on a quaternized cellulose support. A sensor for hydrogen peroxide and nitric oxide.
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Articles

2D and 3D scaffold patterning techniques can be applied in the presence of cells using poly(ethylene glycol) (PEG)-based hydrogels. These methods can be applied to any optically transparent, photoactive substrate.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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