475696

Poly(ethylene glycol) diglycidyl ether

average M_n 500

• Synonym(s): Diepoxy PEG, PEG diglycidyl ether, Polyoxyethylene bis(glycidyl ether)
• Linear Formula: C₃H₅O₂-(C₂H₄O)_n-C₃H₅O
• CAS Number: 26403-72-5
• NACRES: NA.23

Properties

• mol wt: average M_n 500
• Quality Level: 200
• reaction suitability: reagent type: cross-linking reagent; reactivity: amine reactive
• refractive index: n20/D 1.47
• Ω-end: glycidyl
• α-end: glycidyl
• polymer architecture: shape: linear; functionality: homobifunctional
• storage temp.: 2-8°C
• InChI: 1S/C8H14O4/c1(9-3-7-5-11-7)2-10-4-8-6-12-8/h7-8H,1-6H2
• InChI key: AOBIOSPNXBMOAT-UHFFFAOYSA-N

Description

General description

Poly(ethylene glycol) diglycidyl ether (PEGDGE) shows highly solubility in water. Hence, it easily undergoes hydrolysis followed by ring cleavage reaction in aqueous solution, yielding hydroxyl group. PEGDGE combines with proteins covalently or non-covalently. PEGDGE is widely used in chemical industries for cross linking and surface modifier.

Application

The high solubility of PEGDGE has been successfully employed to immobilize glucose oxidase, d-amino acid oxidase and glutamate oxidase. It may be used as a component for the development of microelectrode biosensors to detect hydrogen peroxide and nitric oxide.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 386.6 °F - closed cup
• Flash Point(C): 197.00 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves