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47618

Sigma-Aldrich

Fmoc-Asp(OtBu)-OH

≥98.0% (HPLC)

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Synonym(s):
Fmoc-L-aspartic acid 4-tert-butyl ester
Empirical Formula (Hill Notation):
C23H25NO6
CAS Number:
Molecular Weight:
411.45
Beilstein:
3635671
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

Quality Level

Assay

≥98.0% (HPLC)

form

powder

optical activity

[α]20/D −24±2°, c = 1% in DMF

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

mp

148-150 °C (dec.)

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

CC(C)(C)OC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C23H25NO6/c1-23(2,3)30-20(25)12-19(21(26)27)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,26,27)/t19-/m0/s1

InChI key

FODJWPHPWBKDON-IBGZPJMESA-N

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1 of 4

This Item
4757947444772011
Fmoc-Asp(OtBu)-OH ≥98.0% (HPLC)

Sigma-Aldrich

47618

Fmoc-Asp(OtBu)-OH

Fmoc-Asp(OAll)-OH ≥98.0% (HPLC)

Sigma-Aldrich

47579

Fmoc-Asp(OAll)-OH

Fmoc-Asp(OtBu)-OSu ≥98.0% (calc. based on dry substance, CN)

Sigma-Aldrich

47444

Fmoc-Asp(OtBu)-OSu

Fmoc-D-Asp(OtBu)-OH 98%

Sigma-Aldrich

772011

Fmoc-D-Asp(OtBu)-OH

form

powder

form

-

form

-

form

powder or crystals

optical activity

[α]20/D −24±2°, c = 1% in DMF

optical activity

[α]20/D −27±2°, c = 1% in DMF

optical activity

[α]20/D −31±1°, c = 1% in DMF

optical activity

-

mp

148-150 °C (dec.)

mp

111-115 °C

mp

128-132 °C

mp

146-151 °C

functional group

Fmoc

functional group

Fmoc

functional group

Fmoc

functional group

Fmoc

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-

General description

Fmoc-Asp(OtBu)-OH also known as Fmoc-L-aspartic acid 4-tert-butyl ester, is a Fmoc protected amino acid, used in solid phase peptide synthesis.

Application

Fmoc-Asp(OtBu)-OH is used to prevent the formation of aspartimide by-products in Fmoc solid phase peptide synthesis.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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