478563

Sigma-Aldrich

2-Amino-6-chloro-9H-purine-9-acetic acid

97%

Empirical Formula (Hill Notation):
C7H6ClN5O2
CAS Number:
Molecular Weight:
227.61
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

97%

mp

>300 °C (lit.)

SMILES string

Nc1nc(Cl)c2ncn(CC(O)=O)c2n1

InChI

1S/C7H6ClN5O2/c8-5-4-6(12-7(9)11-5)13(2-10-4)1-3(14)15/h2H,1H2,(H,14,15)(H2,9,11,12)

InChI key

LRZBBTTUKFVUMZ-UHFFFAOYSA-N

General description

2-Amino-6-chloro-9H-purine-9-acetic acid is a purine derivative.

Application

2-Amino-6-chloro-9H-purine-9-acetic acid may be used as starting material in the synthesis of:
  • 6-decyloxy substituted purine intermediates
  • 6-decylthio substituted purine intermediates
  • 6-decyloxy or 6-decylthio-9-phenylalanine/serine or alanine-substituted purine derivatives
  • 2,6-diaminopurine monomer

Packaging

1 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Damian Ackermann et al.
Nucleic acids research, 41(8), 4729-4739 (2013-02-28)
The structural reorganization of nanoscale DNA architectures is a fundamental aspect in dynamic DNA nanotechnology. Commonly, DNA nanoarchitectures are reorganized by means of toehold-expanded DNA sequences in a strand exchange process. Here we describe an unprecedented, toehold-free switching process that...
Ashish K Pathak et al.
Bioorganic & medicinal chemistry, 21(7), 1685-1695 (2013-02-26)
6-Oxo and 6-thio analogs of purine were prepared based on the initial activity screening of a small, diverse purine library against Mycobacterium tuberculosis (Mtb). Certain 6-oxo and 6-thio-substituted purine analogs described herein showed moderate to good inhibitory activity. N(9)-substitution apparently...

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