Miriam Tomasch et al.
Frontiers in systems neuroscience, 6, 14-14 (2012-04-04)
Novel fluorescent chalcone-based ligands at human histamine H(3) receptors (hH(3)R) have been designed, synthesized, and characterized. Compounds described are non-imidazole analogs of ciproxifan with a tetralone motif. Tetralones as chemical precursors and related fluorescent chalcones exhibit affinities at hH(3)R in...
Syntheses and beta-adrenoceptor activities of 2-alkylamino-6-hydroxy-5-hydroxymethyl-1,2,3,4-tetrahydro-1-naphthalenols.
H Sugihara et al.
Chemical & pharmaceutical bulletin, 25(11), 2988-3002 (1977-11-01)
Ewelina van Wenum et al.
The Journal of organic chemistry, 78(18), 9102-9112 (2013-09-07)
Silybin (SIL) and 2,3-dehydrosilybin (DHS) are constituents of milk thistle extract (silymarin) applied in the treatment of cirrhosis, hepatitis, and alcohol-induced liver disease. The molecular mechanism of their action is usually connected with antioxidant action. However, despite experimental and theoretical...