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481181

Sigma-Aldrich

Silver(I) sulfadiazine

98%

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Synonym(s):
Silver sulfadiazine, Sulfadiazine silver
Empirical Formula (Hill Notation):
C10H9AgN4O2S
CAS Number:
Molecular Weight:
357.14
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

Quality Level

assay

98%

form

powder

mp

285 °C (dec.) (lit.)

SMILES string

Nc1ccc(cc1)S(=O)(=O)N([Ag])c2ncccn2

InChI

1S/C10H9N4O2S.Ag/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1

InChI key

UEJSSZHHYBHCEL-UHFFFAOYSA-N

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1 of 4

This Item
PHR2654920991921017
vibrant-m

481181

Silver(I) sulfadiazine

vibrant-m

PHR2654

Silver Sulfadiazine

vibrant-m

920991

Silver(I) carbonate

vibrant-m

921017

Silver (I) Acetate

assay

98%

assay

-

assay

≥99.9% trace metals basis

assay

≥99.9% trace metals basis

Quality Level

100

Quality Level

300

Quality Level

200

Quality Level

200

mp

285 °C (dec.) (lit.)

mp

285 °C (dec.) (lit.)

mp

210 °C (dec.) (lit.)

mp

-

Application

Silver(I) sulfadiazine (AgSD) is popularly used for treating second-degree burn wounds as it acts as an antimicrobial agent and prevents infections. Silver sulfadiazine-impregnated polyurethane (PU) foam, chitosan/chondroitin sulfate films may be used for wound dressing.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2


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Silver sulfadiazine loaded chitosan/chondroitin sulfate films for a potential wound dressing application
Fajardo AR, et al.
Materials Science & Engineering. C, Materials For Biological Applications, 33(2), 588-595 (2013)
Clinical experience with silver sulfadiazine, a new topical agent for control of pseudomonas infections in burns
Stanford, W, et al.
The Journal of Trauma and Acute Care Surgery, 9(5), 377-388 (1969)
[Modern possibilities of the local treatment of children with burn wounds].
L I Budkevich et al.
Khirurgiia, (10)(10), 48-51 (2012-12-14)
Chia-Yu Chu et al.
PloS one, 7(6), e38360-e38360 (2012-06-14)
Silver nanoparticles supported on nanoscale silicate platelets (AgNP/NSP) possess interesting properties, including a large surface area and high biocide effectiveness. The nanohybrid of AgNP/NSP at a weight ratio 7/93 contains 5-nm Ag particles supported on the surface of platelets with
Steven L Percival et al.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 20(5), 647-657 (2012-09-19)
Both chronic and acute dermal wounds are susceptible to infection due to sterile loss of the innate barrier function of the skin and dermal appendages, facilitating the development of microbial communities, referred to as biofilms, within the wound environment. Microbial

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