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487090

Sigma-Aldrich

Water-18O

99 atom % 18O

Synonym(s):

18O Labeled water

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1 G
$356.00

$356.00

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1 G
$356.00

About This Item

Linear Formula:
H218O
CAS Number:
Molecular Weight:
20.02
MDL number:
UNSPSC Code:
12142200
PubChem Substance ID:
NACRES:
NA.12

$356.00

List Price$1,780.00Save 80%

In StockDetails


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description

Normalized with respect to hydrogen

Quality Level

isotopic purity

99 atom % 18O

form

liquid

bp

100 °C (lit.)

mp

0 °C (lit.)

density

1.11 g/mL at 20 °C (lit.)

mass shift

M+2

storage temp.

room temp

SMILES string

[18OH2]

InChI

1S/H2O/h1H2/i1+2

InChI key

XLYOFNOQVPJJNP-NJFSPNSNSA-N

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1 of 4

This Item
332089329878902187
Water-18O 99 atom % 18O

487090

Water-18O

Water-18O 10 atom % 18O

332089

Water-18O

Water-18O (for PET), 97 atom % 18O

329878

Water-18O

Water-18O (for PET), ≥98 atom % 18O

902187

Water-18O

mass shift

M+2

mass shift

M+2

mass shift

M+2

mass shift

M+2

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

liquid

form

liquid

form

liquid

form

liquid

density

1.11 g/mL at 20 °C (lit.)

density

1.11 g/mL at 20 °C (lit.)

density

1.11 g/mL at 20 °C (lit.)

density

1.11 g/mL at 20 °C (lit.)

bp

100 °C (lit.)

bp

100 °C (lit.)

bp

100 °C (lit.)

bp

100 °C (lit.)

General description

H2180 is isotopically modified compound consisting of two hydrogen atoms covalently bonded to oxygen-18. It is most convenient to store, transport and use Oxygen-18 in the form of water enriched with this isotope.

Application

O-18 enriched water is used in Positron-Emission Tomography (PET), a nuclear imaging technique that is used to observe metabolic processes in the body as an aid to the diagnosis of disease such as tumors, staging of cancer, metastasis, dementia, etc. H2180 is currently the only potential universal bacterial substrate suitable for stable isotope probing (SIP). It has been used in the quantification of population-specific growth dynamics in benthic bacterial communities in response to changing redox conditions.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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H H Coenen et al.
Nuclear medicine and biology, 37(7), 727-740 (2010-09-28)
Positron emission tomography (PET) is a rapidly expanding clinical modality worldwide thanks to the availability of compact medical cyclotrons and automated chemistry for the production of radiopharmaceuticals. There is an armamentarium of fluorine-18 ((18)F) tracers that can be used for
Elizabeth A Rettedal et al.
MicrobiologyOpen, 4(2), 208-219 (2015-02-05)
Current limitations in culture-based methods have lead to a reliance on culture-independent approaches, based principally on the comparative analysis of primary semantides such as ribosomal gene sequences. DNA can be remarkably stable in some environments, so its presence does not
Ömer K Coskun et al.
The ISME journal, 13(6), 1546-1559 (2019-02-21)
The benthos in estuarine environments often experiences periods of regularly occurring hypoxic and anoxic conditions, dramatically impacting biogeochemical cycles. How oxygen depletion affects the growth of specific uncultivated microbial populations within these diverse benthic communities, however, remains poorly understood. Here

Questions

  1. Mit welcher analytischen Methode wird die Isotopenreinheit geprüft?

    1 answer
    1. The method to determine isotopic purity is Mass Spectrometry. This product is an M-Clarity level 200 item. The analytical methods are considered proprietary. Please see the link below to a sample Certificate of Analysis that notes they method:
      https://www.sigmaaldrich.com/certificates/COFA/48/487090/487090-BULK_______MBBC8728__.pdf

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