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488577

Cholesterol-2,2,3,4,4,6-d6

97 atom % D, 98% (CP)

Synonym(s):

3β-Hydroxy-5-cholestene-2,2,3,4,4,5-d6, 5-Cholesten-3β-ol-2,2,3,4,4,5-d6, Deuterated cholesterol

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100 MG

$1,340.00

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About This Item

Empirical Formula (Hill Notation):
C27D6H40O
CAS Number:
92543-08-3
Molecular Weight:
392.69
NACRES:
NA.12
PubChem Substance ID:
24872407
UNSPSC Code:
12352211
MDL number:
MFCD00209699
Isotopic purity:
97 atom % D
Assay:
98% (CP)
Mass shift:
M+6

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InChI

1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1/i9D,13D2,17D2,21D

SMILES string

[2H]C1=C2C([2H])([2H])[C@@]([2H])(O)C([2H])([2H])C[C@]2(C)[C@H]3CC[C@]4(C)[C@H](CC[C@H]4[C@@H]3C1)[C@H](C)CCCC(C)C

InChI key

HVYWMOMLDIMFJA-HHPLMCQASA-N

isotopic purity

97 atom % D

assay

98% (CP)

optical activity

[α]20/D -40°, c = 2 in chloroform

technique(s)

mass spectrometry (MS): suitable

bp

360 °C (lit.)

mp

147-149 °C (lit.)

density

1.088 g/mL at 25 °C

mass shift

M+6

storage temp.

−20°C

Quality Level

200

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This Item
749478709549723266
Cholesterol-2,2,3,4,4,6-d6 97 atom % D, 98% (CP)

Sigma-Aldrich

488577

Cholesterol-2,2,3,4,4,6-d6

Cholesterol-2,3,4-13C3 99 atom % 13C, 98% (CP)

Sigma-Aldrich

749478

Cholesterol-2,3,4-13C3

Dehydroepiandrosterone-2,2,3,4,4,6-d6 97 atom % D, 98% (CP)

Sigma-Aldrich

709549

Dehydroepiandrosterone-2,2,3,4,4,6-d6

Dehydroepiandrosterone-2,2,3,4,4,6-d6 sulfate sodium salt 97 atom % D, 98% (CP)

Sigma-Aldrich

723266

Dehydroepiandrosterone-2,2,3,4,4,6-d6 sulfate sodium salt

assay

98% (CP)

assay

98% (CP)

assay

98% (CP)

assay

98% (CP)

technique(s)

mass spectrometry (MS): suitable

technique(s)

mass spectrometry (MS): suitable

technique(s)

mass spectrometry (MS): suitable

technique(s)

mass spectrometry (MS): suitable

isotopic purity

97 atom % D

isotopic purity

99 atom % 13C

isotopic purity

97 atom % D

isotopic purity

97 atom % D

mass shift

M+6

mass shift

M+3

mass shift

M+6

mass shift

M+6

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

bp

360 °C (lit.)

bp

-

bp

-

bp

-

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MBBF0559
MBBD5613
MBBC3614
MBBB5074V
MBBB4551V

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Alice Passoni et al.
ACS chemical neuroscience, 11(3), 367-372 (2019-12-21)
The current pharmacological treatment of Huntington's disease (HD) is palliative, and therapies to restore functions in patients are needed. One of the pathways affected in HD involves brain cholesterol (Chol) synthesis, which is essential for optimal synaptic transmission. Recently, it
Matteo Ludovici et al.
Scientific reports, 8(1), 11500-11500 (2018-08-02)
The skin surface lipids (SSL) result from the blending of sebaceous and epidermal lipids, which derive from the sebaceous gland (SG) secretion and the permeability barrier of the stratum corneum (SC), respectively. In humans, the composition of the SSL is
David Wheeler et al.
Brain : a journal of neurology, 131(Pt 11), 3092-3102 (2008-09-06)
Maintaining the appropriate complement and content of lipids in cellular membranes is critical for normal neural function. Accumulating evidence suggests that even subtle perturbations in the lipid content of neurons and myelin can disrupt their function and may contribute to
Wenxu Zhou et al.
Journal of lipid research, 61(2), 192-204 (2019-09-25)
Primitive sterol evolution plays an important role in fossil record interpretation and offers potential therapeutic avenues for human disease resulting from nematode infections. Recognizing that C4-methyl stenol products [8(14)-lophenol] can be synthesized in bacteria while C4-methyl stanol products (dinosterol) can
Yasuyo Okada et al.
Carbohydrate research, 455, 54-61 (2017-11-25)
We aimed to investigate whether 6-O-α-maltosyl-β-cyclodextrin (Mal-βCD) is incorporated into cells and lysosomes during the release of unesterified cholesterol in Npc1-deficient Chinese hamster ovary (CHO) cells (Npc1 KO cells) and CHO-JP17 cells (JP17 cells). Internalization of Mal-βCD in cells and lysosomes and
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