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MilliporeSigma

495212

4-Hydroxy-3-nitropyridine

98%

Synonym(s):

3-Nitro-4-pyridinol

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5 G

$62.60

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About This Item

Empirical Formula (Hill Notation):
C5H4N2O3
CAS Number:
Molecular Weight:
140.10
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
98%

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InChI

1S/C5H4N2O3/c8-5-1-2-6-3-4(5)7(9)10/h1-3H,(H,6,8)

SMILES string

Oc1ccncc1[N+]([O-])=O

InChI key

YUWOLBZMQDGRFV-UHFFFAOYSA-N

assay

98%

mp

285 °C (dec.) (lit.)

functional group

nitro

Quality Level

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H48808658448162604
assay

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assay

97%

assay

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assay

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Quality Level

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Quality Level

100

Quality Level

100

Quality Level

100

mp

285 °C (dec.) (lit.)

mp

188-191 °C (lit.)

mp

246-250 °C

mp

85-87 °C (lit.)

functional group

nitro

functional group

-

functional group

bromo, nitro

functional group

nitrile

General description

4-Hydroxy-3-nitropyridine can be synthesized by the nitration of 4-hydroxypyridine.[1]

Application

4-Hydroxy-3-nitropyridine may be used in the synthesis of 4-ethoxy-3-nitropyridine by treating with phosphorus pentachloride (PCl5) followed by ethanol.[1] It may also be used to prepare 4-chloro-3-nitropyridine by treating with PCl5-POCl3 (phosphorus oxychloride).[2]

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Use of the Graebe-Ullmann reaction in the synthesis of 8-methyl-γ-carboline and isomeric aromatic aza-γ-carbolines.
Alekseev RS, et al.
Chemistry of Heterocyclic Compounds, 48(8), 1235-1250 (2012)
Unambiguous structural assignment of monoanils of 3,4-pyridinediamine via regioselective synthesis.
Dubey PK, et al.
ARKIVOC (Gainesville, FL, United States), 13, 137-144 (2008)

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