516732

Sigma-Aldrich

2-Mercaptoethanol

Synonym(s):
β-Mercaptoethanol, BME, 2ME, Thioethylene glycol, 2-Hydroxyethylmercaptan
Linear Formula:
HSCH2CH2OH
CAS Number:
Molecular Weight:
78.13
Beilstein/REAXYS Number:
773648
EC Number:
MDL number:

vapor density

2.69 (vs air)

vapor pressure

1 mmHg ( 20 °C)

expl. lim.

18 %

concentration

14.3 M (pure liquid)

refractive index

n20/D 1.500 (lit.)

bp

157 °C (lit.)

density

1.114 g/mL at 25 °C (lit.)

SMILES string

OCCS

InChI

1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2

InChI key

DGVVWUTYPXICAM-UHFFFAOYSA-N

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Application

BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

Legal Information

Product of Arkema

Signal Word

Danger

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 2966 6.1 / PGII

WGK Germany

WGK 3

Flash Point(F)

165.2 °F - closed cup

Flash Point(C)

74 °C - closed cup

Certificate of Analysis

Certificate of Origin

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