519707

Sigma-Aldrich

8-(Tosylamino)quinoline

97%

Synonym(s):
N-(8-Quinolyl)-p-toluenesulfonamide
Empirical Formula (Hill Notation):
C16H14N2O2S
CAS Number:
Molecular Weight:
298.36
Beilstein/REAXYS Number:
264159
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

97%

mp

154-158 °C (lit.)

SMILES string

Cc1ccc(cc1)S(=O)(=O)Nc2cccc3cccnc23

InChI

1S/C16H14N2O2S/c1-12-7-9-14(10-8-12)21(19,20)18-15-6-2-4-13-5-3-11-17-16(13)15/h2-11,18H,1H3

InChI key

ZSMKPYXVUIWTCT-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

V D Bovt et al.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 47(3), 54-57 (2001-08-25)
Alcohol dependence development is accompanied by zinc content decrease in the hippocampus. Young age, repeated physical loads and immobilization are factors, that promote such changes development in more expressed degree.
E D Gol'dberg et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 43-45 (1991-07-01)
The dynamics of changes of the Zn content in the pancreatic islets of rabbits after dithizon injection was studied. The amount of this metal in the islets reduced due to destruction of the cells and under the effect of high...
E D Gol'dberg et al.
Biulleten' eksperimental'noi biologii i meditsiny, 111(2), 135-137 (1991-02-01)
The injections of diabetogenic drugs to rabbits induced a decrease in zinc and calcium content in B insulocytes dependent on the degree of these cells damage and hyperglycemia. The content of these metals in A insulocytes was not significantly altered...
V A Ieshchenko et al.
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 47(2), 66-69 (2001-06-08)
Zinc content in pancreatic islet cells and hippocampus was studied with the aid of highly sensitive selective cytochemical reaction of 8-(p-toluensulfonylamino)-quinoline. It was shown that the factors stimulating B-insulocyte secretory activity induced the decrease of this metal concentrations in the...
J A Lazaris et al.
Endocrinologia experimentalis, 15(2), 99-109 (1981-01-01)
Diabetogenic effects of various analogues of 8-aminoquinoline were studied. Out of 10 compounds investigated only three showed diabetogenic properties: 8-(p-tolylsulfonylamino)-quinoline, 8-(p-benzenesulfonylamino)-quinoline and 8-(p-methylsulfonylamino)-quinoline. After the injection of these compounds a long term persistent hyperglycemia took place in rabbits and also...

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