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540021

Sigma-Aldrich

(S)-(−)-Propylene oxide

99%

Synonym(s):

(S)-(−)-1,2-Epoxypropane, (S)-(−)-Methyloxirane

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5 G
$185.00
25 G
$359.00

$185.00


Estimated to ship onJuly 07, 2025Details


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5 G
$185.00
25 G
$359.00

About This Item

Empirical Formula (Hill Notation):
C3H6O
CAS Number:
Molecular Weight:
58.08
Beilstein/REAXYS Number:
79765
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

$185.00


Estimated to ship onJuly 07, 2025Details


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vapor density

2 (vs air)

Quality Level

vapor pressure

8.59 psi ( 20 °C)

assay

99%

autoignition temp.

1378 °F

expl. lim.

37 %

refractive index

n20/D 1.366 (lit.)

bp

33-34 °C (lit.)

density

0.829 g/mL at 20 °C (lit.)

functional group

ether

SMILES string

C[C@H]1CO1

InChI

1S/C3H6O/c1-3-2-4-3/h3H,2H2,1H3/t3-/m0/s1

InChI key

GOOHAUXETOMSMM-VKHMYHEASA-N

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This Item
540048256323540102
assay

99%

assay

99%

assay

99%

assay

98%

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

density

0.829 g/mL at 20 °C (lit.)

density

0.829 g/mL at 20 °C (lit.)

density

0.992 g/mL at 25 °C (lit.)

density

1.051 g/mL at 25 °C (lit.)

refractive index

n20/D 1.366 (lit.)

refractive index

n20/D 1.366 (lit.)

refractive index

n20/D 1.520 (lit.)

refractive index

n20/D 1.535 (lit.)

bp

33-34 °C (lit.)

bp

33-34 °C (lit.)

bp

94-95 °C/10 mmHg (lit.)

bp

192-194 °C (lit.)

vapor density

2 (vs air)

vapor density

-

vapor density

-

vapor density

-

Application

  • (S)-(−)-Propylene oxide undergoes ring-opening upon treating with nucleophiles such as Grignard reagents or organolithium compounds to yield corresponding secondary alcohols.[1][2]
  • It can be used in the synthesis of ligands to prepare of Pb(II) based coordination nets for the fabrication of white light-emitting diode materials.[1]
  • It is a key starting material for the total synthesis of arenolide[2] and (+)-aspicilin.[3]

Legal Information

Manufactured under license by Sterling Pharma Solutions Limited, using Jacobsen HKR technology.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Flam. Liq. 1 - Muta. 1B - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

-34.6 °F - closed cup

flash_point_c

-37 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves


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Questions

  1. Can we vent out PO to safe location in atmosphere. We are unloading PO through jetty by 12 " Pipeline. Can Thermal Relief Valve and PSV (designed for Fire case) outlet be send to atmosphere at safe height ?

    1 answer
    1. It is possible to vent this product in a safe atmosphere. As listed on the Safety Data Sheet, use only outdoors or in a well-ventilated area.

      Please read carefully through the Safety Data Sheet for this product:
      https://www.sigmaaldrich.com/sds/aldrich/540021

      For further questions or concerns, please navigate to the link https://www.sigmaaldrich.com/techservice, and click on "Product Technical Inquiries" under the Products Section with all the required information so that a member of the Technical Service team can reach out to assist further. Thank you.

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