542342

Sigma-Aldrich

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)

average Mn ~14,600

Synonym(s):
PEG-PPG-PEG, Pluronic® F-108
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

Quality Level

vapor density

>1 (vs air)

vapor pressure

<0.3 mmHg ( 20 °C)

mol wt

average Mn ~14,600

composition

PEG, 82.5 wt. %

pH

6.0-7.4 (2.5% in H2O)

surface tension

41 dyn/cm, 25 °C, 0.1 wt. % in H2O

viscosity

2,800 cP(77 °C, Brookfield)(lit.)

transition temp

cloud point >100 °C (1 wt. % aqueous solution)
Tm (DSC) 60 °C (at peak)

HLB

>24.0

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

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General description

Pluronic® F108 is a tri block copolymer and a terminal primary dihydroxy-functional oligomer. It behaves as a nonionic surfactant. It is a surface active material whose properties are dependent on the hydrophilic (EO)/hydrophobic (PO) ratio. High EO content gives better o/w stabilizers.

Application

Hard and soft surface cleaners, defoamers in coatings and water treatment. Lubricant in metal working, anti-foaming aid and extender for linear and cross-linked polyesters and polyurethanes.
Pluronic® F108 was used as a surfactant in a medium to prevent the cells from sticking to the surface of a microfluidic device.{7}-{11}Pluronic may be potentially useful as a pathogen detector. It was used in the analysis of microbial community and genotyping single nucleotide polymorphisms (SNPs).{9} The triblock copolymer was used as a pore template for the fabrication of porous carbons and carbon/silica composite.{10}

Packaging

250 g in poly bottle
1 kg in poly bottle

Features and Benefits

Surface active material whose properties are dependent on the hydrophilic (EO)/hydrophobic (PO) ratio. High EO content gives better o/w stabilizers.

Physical form

Terminal primary dihydroxy-functional oligomer.

Legal Information

Pluronic is a registered trademark of BASF

RIDADR

NONH for all modes of transport

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

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This paper describes mammary organoids with a basal-in phenotype where the basement membrane is located on the interior surface of the organoid. A key materials consideration to induce this basal-in phenotype is the use of a minimal gel scaffold that...
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The maintenance of precise cell volume is critical for cell survival. Changes in extracellular osmolarity affect cell volume and may impact various cellular processes such as mitosis, mitochondrial functions, DNA repair as well as cell migration and proliferation. Much of...
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Understanding how forces orchestrate tissue formation requires technologies to map internal tissue stress at cellular length scales. Here, we develop ultrasoft mechanosensors that visibly deform under less than 10 Pascals of cell-generated stress. By incorporating these mechanosensors into multicellular spheroids...
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