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558958

4-Chlorobenzyl bromide

97%

Synonym(s):

α-Bromo-p-chlorotoluene, 1-(Bromomethyl)-4-chlorobenzene, 1-Chloro-4-bromomethylbenzene, p-Chlorobenzyl bromide

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25 g

Estimated to ship onMay 04, 2026fromMILWAUKEE

$417.00
100 g

Estimated to ship onMay 04, 2026fromMILWAUKEE

$950.00

About This Item

Linear Formula:
ClC6H4CH2Br
CAS Number:
622-95-7
Molecular Weight:
205.48
NACRES:
NA.22
PubChem Substance ID:
24879785
UNSPSC Code:
12352100
EC Number:
210-760-7
MDL number:
MFCD00040714
Assay:
97%
Form:
solid

$417.00

Estimated to ship onMay 04, 2026Details

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Quality Level

200

assay

97%

form

solid

mp

48-52 °C (lit.)

functional group

bromo, chloro

SMILES string

Clc1ccc(CBr)cc1

InChI

1S/C7H6BrCl/c8-5-6-1-3-7(9)4-2-6/h1-4H,5H2

InChI key

KQNBRMUBPRGXSL-UHFFFAOYSA-N

General description

4-Chlorobenzyl bromide undergoes carbonylation in the presence of dimer of chloro(1,5-cyclooctadiene)rhodium(I) to yield the corresponding phenylacetic acid. It can be synthesized by reacting 4-chlorobenzyl alcohol with bromodimethylsulfonium bromide (BDMS) It can also be synthesized by refluxing a mixture of 4-chlorobenzaldehyde, chlorotrimethylsilane, 1,1,3,3-tetramethyldisiloxane and lithium bromide.

Application

4-Chlorobenzyl bromide may be used to synthesize:

  • 1-(4-chlorobenzyl)-2-(pyrrolidin-1-yl-methyl)-1H-benzimidazole dihydrochloride
  • 1-[1-[2-[(4-chlorobenzyl)thio]phenyl]vinyl]-1H-imidazole
  • 6-[4-(4-chlorobenzyl)piperazinyl]chromane
  • N,N′-bis(4-chlorobenzyl)piperazine
  • N-(4-chlorobenzyl)piperazine

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1 of 1

This Item
136727529990112216
4-Chlorobenzyl bromide 97%

Sigma-Aldrich

558958

4-Chlorobenzyl bromide

3-Chlorobenzyl bromide 97%

Sigma-Aldrich

136727

3-Chlorobenzyl bromide

4-Bromomethyl benzoyl bromide 96%

Sigma-Aldrich

529990

4-Bromomethyl benzoyl bromide

4-Chlorobenzaldehyde 97%

Sigma-Aldrich

112216

4-Chlorobenzaldehyde

assay

97%

assay

97%

assay

96%

assay

97%

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

form

solid

form

liquid

form

-

form

solid

mp

48-52 °C (lit.)

mp

-

mp

57-61 °C (lit.)

mp

45-50 °C (lit.)

functional group

bromo, chloro

functional group

bromo, chloro

functional group

acyl bromide, bromo

functional group

aldehyde, chloro

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL4281
BCCH4241
BCCJ5952
BCCJ5951
BCCC8006

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Gazi S and Ananthakrishnan R
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Aizpurua.MJ, et al.
Canadian Journal of Chemistry, 64(12), 2342-2347 (1986)
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Global Trade Item Number

SKUGTIN
558958-25G04061833548417
558958-100G04061833548400

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