576662

Indole-6-carboxylic acid

97%

• Synonym(s): 6-Carboxyindole
• Empirical Formula (Hill Notation): C₉H₇NO₂
• CAS Number: 1670-82-2
• Molecular Weight: 161.16
• Beilstein: 123991
• MDL number: MFCD00210441
• PubChem Substance ID: 24880873
• NACRES: NA.22

Properties

• Assay: 97%
• mp: 249-253 °C (lit.)
• SMILES string: OC(=O)c1ccc2cc[nH]c2c1
• InChI: 1S/C9H7NO2/c11-9(12)7-2-1-6-3-4-10-8(6)5-7/h1-5,10H,(H,11,12)
• InChI key: GHTDODSYDCPOCW-UHFFFAOYSA-N

Description

Application

• Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase
• Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors
• Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway
• Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity
• Reactant for preparation of pyridinyl carboxylates via esterification with chlorohydroxypyridine as SARS-CoV 3CL proinhibitors
• Reactant for preparation of (indolecarbonyl)-D-phenylglycinamide amides as factor Xa inhibitors

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves