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602892

Sigma-Aldrich

Oxygen-18O2

99 atom % 18O, 99% (CP)

Linear Formula:
18O2
CAS Number:
Molecular Weight:
36.00
MDL number:
PubChem Substance ID:
NACRES:
NA.12

vapor density

1.11 (vs air)

Quality Level

isotopic purity

99 atom % 18O

Assay

99% (CP)

form

gas

technique(s)

PET imaging: suitable

bp

−183 °C (lit.)

mp

−218 °C (lit.)

mass shift

M+4

SMILES string

[18O]=[18O]

InChI

1S/O2/c1-2/i1+2,2+2

InChI key

MYMOFIZGZYHOMD-XPULMUKRSA-N

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1 of 4

This Item
490474602876602922
Oxygen-18O2 99 atom % 18O, 99% (CP)

Sigma-Aldrich

602892

Oxygen-18O2

Oxygen-18O2 97 atom % 18O

Sigma-Aldrich

490474

Oxygen-18O2

Oxygen-18O2 90 atom % 18O

Sigma-Aldrich

602876

Oxygen-18O2

Oxygen-18O2 25 atom % 18O (random)

Sigma-Aldrich

602922

Oxygen-18O2

isotopic purity

99 atom % 18O

isotopic purity

97 atom % 18O

isotopic purity

90 atom % 18O

isotopic purity

25 atom % 18O (random)

assay

99% (CP)

assay

99% (CP)

assay

-

assay

-

form

gas

form

-

form

gas

form

gas

technique(s)

PET imaging: suitable

technique(s)

-

technique(s)

-

technique(s)

-

bp

−183 °C (lit.)

bp

−183 °C (lit.)

bp

−183 °C (lit.)

bp

−183 °C (lit.)

General description

Oxygen-18O2 is a naturally occurring stable isotope of oxygen. Natural abundance of 18O2 containing at least 99 atom % O-18.

Application

18O2 isotopic labelling was employed, in conjunction with time-of-flight secondary ion mass spectrometry, to characterize and elucidate the parts of the degradation mechanisms induced by molecular oxygen. Using 18O2 as a label, it is possible to study collagen degradation with this non-reutilized label and so avoid the large errors that are introduced by the recycling of other labels.
Oxygen-18O2 can be used to study the kinetic and functional analyses in photosynthesis research. It is used to estimate the role of oxygen in the vitamin-K dependent carboxylation reaction. Also used to measure the amount of oxygen produced by the etching a quartz tube with SF6 plasma.

Packaging

1 L quantity is packaged in a 450 mL carbon steel lecture bottle with brass CGA 110/180 valve. Nominal gas pressure at 21ºC is 20 psig for 1 L. This pressure is slightly above atmospheric pressure. Care must be taken when extracting this product from the cylinder.
All gas volumes are quoted at Standard Temperature and Pressure (STP) and not at Normal Temperature and Pressure (NTP). One STP Liter is 7.7% more gas than one NTP Liter.

Recommended products

Brass hose adapter Z146811 or brass body mini gas regulator Z513539 is recommended for 500 mL Sure/Pac cylinder (U.S only). For 1 L cylinder, either stainless steel control valve Z146951 or Z187224 is recommended.
PTFE sealing washers GCA inlet size 180 Z146994
PTFE sealing washers CGA inlet size 110 Z146986

hose barb

Product No.
Description
Pricing

regulator

Product No.
Description
Pricing

Pictograms

Flame over circleGas cylinder

Signal Word

Danger

Hazard Statements

Hazard Classifications

Ox. Gas 1 - Press. Gas Compr. Gas

Storage Class Code

2A - Gases

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

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Sigma-Aldrich

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Sigma-Aldrich

329886

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Oxygen-18O2 10 atom % 18O (random)

Sigma-Aldrich

602914

Oxygen-18O2

Water-18O (for PET), ≥98 atom % 18O

Sigma-Aldrich

902187

Water-18O

Dmitriy Shevela et al.
Frontiers in plant science, 4, 473-473 (2013-12-11)
Monitoring isotopic compositions of gaseous products (e.g., H2, O2, and CO2) by time-resolved isotope-ratio membrane-inlet mass spectrometry (TR-IR-MIMS) is widely used for kinetic and functional analyses in photosynthesis research. In particular, in combination with isotopic labeling, TR-MIMS became an essential
Rachelle A S Lemke et al.
The Journal of biological chemistry, 295(29), 9786-9801 (2020-05-22)
Fatty acids play many important roles in cells and also in industrial processes. Furan fatty acids (FuFAs) are present in the lipids of some plant, fish, and microbial species and appear to function as second messengers in pathways that protect
J A Molnar et al.
The Biochemical journal, 250(1), 71-76 (1988-02-15)
To explore the effects of growth retardation, caused by restricted protein intake, on collagen turnover in the whole skin, Sprague-Dawley rats (n = 20) were labelled with 18O2 and fed on either an adequate (18%) or a low (3%) lactalbumin
Catherine Fenselau et al.
Journal of proteome research, 8(5), 2140-2143 (2009-04-03)
Enzyme-catalyzed 18O2-labeling offers a universal strategy for uniform labeling of all peptides from any kind of proteins, including post-translationally modified proteins. It is applicable to clinical samples with unrivaled sensitivity. This review discusses strengths and limitations, and advocates the separation
Sui So et al.
Physical chemistry chemical physics : PCCP, 16(45), 24954-24964 (2014-10-18)
β-Hydroxyperoxyl radicals are formed during atmospheric oxidation of unsaturated volatile organic compounds such as isoprene. They are intermediates in the combustion of alcohols. In these environments the unimolecular isomerization and decomposition of β-hydroxyperoxyl radicals may be of importance, either through

Related Content

Stable Isotopes in PET (Positron Emission Tomography)

Labeled isotopes used as target materials in imaging have provided insights into the various mechanisms of human physiology and have lead to treatments for diseases. Water-18O is used for the production of 18F radionuclides, such as 18FDG (Fluoro-deoxyglucose). 18FDG used in PET and with other imaging technologies, such as CT/SPECT, has led to the diagnosis and treatment of a wide range of diseases, including lung, liver, and brain tumors, epilepsy, and Alzheimer’s.

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