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605239

Sigma-Aldrich

L-Leucine-13C6

98 atom % 13C, 95% (CP)

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Synonym(s):
SILAC Amino Acid, (S)-2-Amino-4-methylpentanoic acid-13C6, 13C Labeled L-leucine
Linear Formula:
(13CH3)213CH13CH213CH(NH2)13CO2H
CAS Number:
Molecular Weight:
137.13
MDL number:
PubChem Substance ID:
NACRES:
NA.12

isotopic purity

98 atom % 13C

Quality Level

Assay

95% (CP)

form

solid

optical activity

[α]25/D +14.5°, c = 2 in 5 M HCl

technique(s)

protein expression: suitable

mp

>300 °C (lit.)

mass shift

M+6

SMILES string

[13CH3][13CH]([13CH3])[13CH2][13C@H](N)[13C](O)=O

InChI

1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1/i1+1,2+1,3+1,4+1,5+1,6+1

InChI key

ROHFNLRQFUQHCH-IQUPZBQQSA-N

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1 of 4

This Item
608068486825608092
L-Leucine-13C6 98 atom % 13C, 95% (CP)

Sigma-Aldrich

605239

L-Leucine-13C6

L-Leucine-13C6,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)

Sigma-Aldrich

608068

L-Leucine-13C6,15N

L-Leucine-5,5,5-d3 99 atom % D

Sigma-Aldrich

486825

L-Leucine-5,5,5-d3

L-Isoleucine-13C6,15N 98 atom % 15N, 98 atom % 13C, 95% (CP)

Sigma-Aldrich

608092

L-Isoleucine-13C6,15N

assay

95% (CP)

assay

95% (CP)

assay

99% (CP)

assay

95% (CP)

form

solid

form

solid

form

solid

form

solid

technique(s)

protein expression: suitable

technique(s)

bio NMR: suitable, protein expression: suitable

technique(s)

protein expression: suitable

technique(s)

bio NMR: suitable, protein expression: suitable

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

168-170 °C (lit.)

mass shift

M+6

mass shift

M+7

mass shift

M+3

mass shift

M+7

General description

Leucine is a non-polar ketogenic amino acid. It can be metabolised to acetoacetate and acetyl coenzyme A. Isotope labeled amino acids are required for the production of isotopically labeled proteins.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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L-Isoleucine-13C6 ≥99 atom % 13C, ≥98% (CP)

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L-Isoleucine-13C6

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Harvey RA, et al.
Biochemistry (Lippincott's illustrated reviews) (2011)
Incorporation of radioactive amino acids into proteins of the microsome fraction of guinea-pig liver in a cell-free system.
SIMKIN JL and WORK TS
The Biochemical Journal, 67, 617-624 (1957)
Isotope labeling for solution and solid-state NMR spectroscopy of membrane proteins.
Verardi R, et al.
Advances in Experimental Medicine and Biology, 992, 35-62 (2012)
Garrett RH and Grisham CM
Biochemistry (2012)
The incorporation of radioactive amino acids into proteins of the microsome fraction of guinea-pig liver at very short time intervals after administration.
Simkin JL and Sutton CR
The Biochemical Journal, 77, 489-492 (1960)

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