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MilliporeSigma

607983

L-Glutamine-13C5,15N2

98 atom % 13C, 98 atom % 15N

Synonym(s):

(S)-2,5-Diamino-5-oxopentanoic acid-13C5-15N2, L-Glutamic acid 5-amide-13C5-15N2, L-Glutamine-ul-13C,15N, 13C and 15N Labeled glutamine

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100 MG

$1,560.00

500 MG

$2,750.00

$1,560.00


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About This Item

Linear Formula:
H215N13CO(13CH2)213CH(15NH2)13CO2H
Molecular Weight:
153.09
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:

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Product Name

L-Glutamine-13C5,15N2, 98 atom % 13C, 98 atom % 15N

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1/i1+1,2+1,3+1,4+1,5+1,6+1,7+1

SMILES string

[15NH2][13C@@H]([13CH2][13CH2][13C]([15NH2])=O)[13C](O)=O

InChI key

ZDXPYRJPNDTMRX-YIDSDQPMSA-N

isotopic purity

98 atom % 13C
98 atom % 15N

assay

95% (CP)

form

solid

optical activity

[α]25/D +33.0°, c = 2 in 5 M HCl

technique(s)

bio NMR: suitable

mp

185 °C (dec.) (lit.)

mass shift

M+7

storage temp.

room temp

Quality Level

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This Item
607851635081604860
technique(s)

bio NMR: suitable

technique(s)

bio NMR: suitable

technique(s)

bio NMR: suitable

technique(s)

-

isotopic purity

98 atom % 13C, 98 atom % 15N

isotopic purity

98 atom % 13C, 98 atom % 15N

isotopic purity

98 atom % 13C, 98 atom % 15N, 96 atom % D

isotopic purity

98 atom % 13C

mass shift

M+7

mass shift

M+6

mass shift

M+17

mass shift

M+5

assay

95% (CP)

assay

95% (CP)

assay

95% (CP)

assay

95% (CP)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

solid

form

solid

form

solid

form

solid

General description

Glutamine is an amino acid with an uncharged polar side chain. It can be catabolized to glutamate and ammonia. Glutamine is the most abundant amino acid in the central nervous system.[1][2] Isotope labeled amino acids are required for the production of isotopically labeled proteins.[3][4][5]

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

related product

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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13C Tracer Studies of Metabolism in Mouse Tumor Xenografts.
Lane AN, et al.
Bio-protocol, 5, bio-protocol (2015)
Wei Yan et al.
Nature cell biology, 20(5), 597-609 (2018-04-18)
Cancer and other cells residing in the same niche engage various modes of interactions to synchronize and buffer the negative effects of environmental changes. Extracellular microRNAs (miRNAs) have recently been implicated in the intercellular crosstalk. Here we show a mechanistic
Stable Isotope Resolved Metabolomics Studies in Ex Vivo TIssue Slices.
Fan TW, et al.
Bio-protocol, 6, e1730-e1730 (2016)
Incorporation of radioactive amino acids into proteins of the microsome fraction of guinea-pig liver in a cell-free system.
SIMKIN JL and WORK TS
The Biochemical Journal, 67, 617-624 (1957)
Manabu Kodama et al.
Nature communications, 11(1), 1320-1320 (2020-03-19)
Glucose metabolism is remodeled in cancer, but the global pattern of cancer-specific metabolic changes remains unclear. Here we show, using the comprehensive measurement of metabolic enzymes by large-scale targeted proteomics, that the metabolism both carbon and nitrogen is altered during

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