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608017

Sigma-Aldrich

L-Phenylalanine-13C9,15N

98 atom % 15N, 98 atom % 13C, 95% (CP), 97% (Chiral Purity)

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Synonym(s):
(S)-2-Amino-3-phenylpropionic acid-13C9,15N, 13C and 15N Labeled L-phenylalanine, SILAC Amino Acid, Phenylalanine-UL-13C,15N
Linear Formula:
13C6H513CH213CH(15NH2)13CO2H
CAS Number:
Molecular Weight:
175.12
MDL number:
PubChem Substance ID:
NACRES:
NA.12

isotopic purity

98 atom % 13C
98 atom % 15N

Quality Level

assay

95% (CP)
97% (Chiral Purity)

form

solid

optical activity

[α]25/D -33.0°, c = 1 in H2O

technique(s)

bio NMR: suitable

mp

270-275 °C (dec.) (lit.)

mass shift

M+10

SMILES string

[15NH2][13C@@H]([13CH2][13c]1[13cH][13cH][13cH][13cH][13cH]1)[13C](O)=O

InChI

1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1/i1+1,2+1,3+1,4+1,5+1,6+1,7+1,8+1,9+1,10+1

InChI key

COLNVLDHVKWLRT-CMLFETTRSA-N

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1 of 4

This Item
651443608068607991
L-Phenylalanine-13C9,15N 98 atom % 15N, 98 atom % 13C, 95% (CP), 97% (Chiral Purity)

608017

L-Phenylalanine-13C9,15N

Fmoc-Phe-OH-13C9,15N 98 atom % 13C, 98 atom % 15N, 98% (CP)

651443

Fmoc-Phe-OH-13C9,15N

L-Leucine-13C6,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)

608068

L-Leucine-13C6,15N

L-Tyrosine-13C9,15N 98 atom % 13C, 98 atom % 15N, 95% (CP)

607991

L-Tyrosine-13C9,15N

isotopic purity

98 atom % 13C, 98 atom % 15N

isotopic purity

98 atom % 13C, 98 atom % 15N

isotopic purity

98 atom % 13C, 98 atom % 15N

isotopic purity

98 atom % 13C, 98 atom % 15N

mass shift

M+10

mass shift

M+10

mass shift

M+7

mass shift

M+10

assay

95% (CP), 97% (Chiral Purity)

assay

98% (CP)

assay

95% (CP)

assay

95% (CP)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

solid

form

solid

form

solid

form

solid

General description

Phenylalanine is an aromatic nonpolar amino acid. Phenylalanine, tyrosine and tryptophan are three amino acids which can absorb ultraviolet radiation above 250nm. Degradation of phenylalanine results in the formation of acetoacetate and fumarate. Isotope labeled amino acids are required for the production of isotopically labeled proteins.

Application

L-Phenylalanine-13C9,15N has been used as a supplement in liquid growth culture of Nostoc species to study the involvement of noc operon (NoA biosynthesis operon) in NoA (nocuolin A) synthesis.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Fmoc-Phe-OH-13C9,15N 98 atom % 13C, 98 atom % 15N, 98% (CP)

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L-Tyrosine-13C9 98 atom % 13C, 95% (CP)

Sigma-Aldrich

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The cyanobacterial metabolite nocuolin a is a natural oxadiazine that triggers apoptosis in human cancer cells.
Voracova K, et al.
PLoS ONE, 12, e0172850-e0172850 (2017)
Incorporation of radioactive amino acids into proteins of the microsome fraction of guinea-pig liver in a cell-free system.
SIMKIN JL and WORK TS
The Biochemical Journal, 67, 617-624 (1957)
Garrett RH and Grisham CM
Biochemistry (2012)
The incorporation of radioactive amino acids into proteins of the microsome fraction of guinea-pig liver at very short time intervals after administration.
Simkin JL and Sutton CR
The Biochemical Journal, 77, 489-492 (1960)
Harvey RA, et al.
Biochemistry (Lippincott's illustrated reviews) (2011)

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