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615862

L-Tryptophan-(indole-d5)

97 atom % D

Synonym(s):

(S)-2-Amino-3-(3-indoyl-d5)propionic acid, L-α-Amino-(3-indole-d5)propionic acid, Deuterated Trp, Deuterated tryptophan, Trp-d5

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500 MG

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About This Item

Empirical Formula (Hill Notation):
C11D5H7N2O2
CAS Number:
62595-11-3
Molecular Weight:
209.26
NACRES:
NA.12
PubChem Substance ID:
24881953
UNSPSC Code:
12352209
MDL number:
MFCD00144688
Isotopic purity:
97 atom % D
Mass shift:
M+5
Form:
solid

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InChI

1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1/i1D,2D,3D,4D,6D

SMILES string

[2H]c1[nH]c2c([2H])c([2H])c([2H])c([2H])c2c1C[C@H](N)C(O)=O

InChI key

QIVBCDIJIAJPQS-HLTLGYGQSA-N

isotopic purity

97 atom % D

form

solid

optical activity

[α]20/D -30.5°, c = 1 in H2O

mp

280-285 °C (dec.) (lit.)

mass shift

M+5

Quality Level

200

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This Item
T3300162698T0254
L-Tryptophan-(indole-d5) 97 atom % D

Sigma-Aldrich

615862

L-Tryptophan-(indole-d5)

DL-Tryptophan ≥99% (HPLC)

Sigma-Aldrich

T3300

DL-Tryptophan

DL-Tryptophan ≥99% (HPLC)

Sigma-Aldrich

162698

DL-Tryptophan

L-Tryptophan reagent grade, ≥98% (HPLC)

Sigma-Aldrich

T0254

L-Tryptophan

mass shift

M+5

mass shift

-

mass shift

-

mass shift

-

isotopic purity

97 atom % D

isotopic purity

-

isotopic purity

-

isotopic purity

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

solid

form

powder

form

powder

form

powder

mp

280-285 °C (dec.) (lit.)

mp

289-290 °C (dec.) (lit.)

mp

289-290 °C (dec.) (lit.)

mp

280-285 °C (dec.) (lit.)

optical activity

[α]20/D -30.5°, c = 1 in H2O

optical activity

-

optical activity

-

optical activity

-

General description

L-Tryptophan-(indole-d5) is an isotopically labeled analogue of L-Tryptophan.

Application

L-Tryptophan-(indole-d5) is used
• in biophysical study for neutron scattering.
• as an internal standard for the investigation of anti-inflammatory activity of low molecular weight fractions.
• in structural elucidation of micronutrients and nutraceutical components presence in food stuffs using LC-MS/MS.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MBBF1259
MBBD0487
MBBC3102
MBBC2509
EB0945

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Valerie Laux et al.
European biophysics journal : EBJ, 37(6), 815-822 (2008-02-16)
We describe methods that have been developed within the ILL-EMBL Deuteration Laboratory for the production of maltose binding protein (MBP) that has been selectively labelled either with deuterated tryptophan or deuterated methionine (single labelling), or both (double labelling). MBP is
Gregory W Thomas et al.
Journal of immunoassay & immunochemistry, 37(1), 55-67 (2015-05-12)
The innate immune system is increasingly being recognized as a critical component in osteoarthritis (OA) pathophysiology. An ex vivo immunoassay utilizing human peripheral blood mononuclear cells (PBMC) was developed in order to assess the OA anti-inflammatory properties of the low
Sara Vitalini et al.
Molecules (Basel, Switzerland), 25(2) (2020-01-17)
Food plants contain hundreds of bioactive phytochemicals arising from different secondary metabolic pathways. Among these, the metabolic route of the amino acid Tryptophan yields a large number of plant natural products with chemically and pharmacologically diverse properties. We propose the

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