637998

Vinylboronic anhydride pyridine complex

95%

• Synonym(s): 2,4,6-Trivinylcyclotriboroxane pyridine complex, Trivinyl-boroxin pyridine complex, Trivinylcyclotriboroxane pyridine complex
• Empirical Formula (Hill Notation): C₆H₉B₃O₃ · C₅H₅N
• CAS Number: 442850-89-7
• Molecular Weight: 240.67
• MDL number: MFCD03839940
• PubChem Substance ID: 24882902
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 95%
• form: solid
• storage temp.: −20°C
• SMILES string: c1ccncc1.C=Cb2ob(C=C)ob(C=C)o2
• InChI: 1S/C6H9B3O3.C5H5N/c1-4-7-10-8(5-2)12-9(6-3)11-7;1-2-4-6-5-3-1/h4-6H,1-3H2;1-5H
• InChI key: YLHJACXHRQQNQR-UHFFFAOYSA-N

Description

Application

Reagent used for

• Suzuki-Miyaura cross-coupling
• Stereoselective synthesis via Palladium-catalyzed carboamination
• Alkyl-connected 2-amino-6-vinylpurine (AVP) crosslinking agent to cytosine base in RNA
• Kaiser oxime resin-derived palladacycle as a recoverable polymeric precatalyst in Suzuki-Miyaura cross-coupling reactions in aqueous media
• Kinetic resolution of phosphoryl and sulfonyl esters of binaphthol derivatives via Pd-catalyzed alcoholysis of their vinyl ethers
• Stereoselective isomerization of N-allyl aziridines into Z-enamines by using rhodium hydride catalysis
• Kinetic resolution of axially chiral biaryl derivatives via palladium/chiral diamine ligand-catalyzed alcoholysis
• Transition metal-catalyzed alkenylation of aziridines, cycloaddition and thermal rearrangement reactions
• Intramolecular Heck reaction strategy for synthesis of functionalized tetrahydroanthracenes

Reagent used for Preparation of

• BACE-1 inhibitors and SAR of cyclic sulfone hydroxyethylamines
• Distorted spiropentanes
• Small molecule bradykinin B2 receptor antagonists in angioedema therapy
• Enol Ethers
• Styryl cyclobutanone

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): 176.0 °F - closed cup
• Flash Point(C): 80 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves