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643459

Sigma-Aldrich

L-Lysine-13C6 hydrochloride

99 atom % 13C, 95% (CP)

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Synonym(s):
SILAC Amino Acid, (S)-2,6-Diaminocaproic acid-13C6, 13C Labeled Lys, 13C Labeled lysine
Linear Formula:
H2N(13CH2)413CH(NH2)13CO2H · HCl
CAS Number:
Molecular Weight:
188.60
MDL number:
PubChem Substance ID:
NACRES:
NA.12

isotopic purity

99 atom % 13C

Quality Level

assay

95% (CP)

form

solid

optical activity

[α]25/D +20.7°, c = 2 in 5 M HCl

technique(s)

protein expression: suitable

mp

263-264 °C (dec.) (lit.)

mass shift

M+6

SMILES string

Cl.N[13CH2][13CH2][13CH2][13CH2][13C@H](N)[13C](O)=O

InChI

1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1/i1+1,2+1,3+1,4+1,5+1,6+1;

InChI key

BVHLGVCQOALMSV-BOBMYJBMSA-N

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1 of 4

This Item
616192609021608041
vibrant-m

643459

L-Lysine-13C6 hydrochloride

vibrant-m

616192

L-Lysine-4,4,5,5-d4 hydrochloride

vibrant-m

609021

L-Lysine-15N2 hydrochloride

vibrant-m

608041

L-Lysine-13C6,15N2 hydrochloride

assay

95% (CP)

assay

98% (CP)

assay

98% (CP)

assay

95% (CP)

mass shift

M+6

mass shift

M+4

mass shift

M+2

mass shift

M+8

technique(s)

protein expression: suitable

technique(s)

protein expression: suitable

technique(s)

bio NMR: suitable, protein expression: suitable

technique(s)

bio NMR: suitable, protein expression: suitable

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

solid

form

solid

form

solid

form

solid

Application

Pulsed Stable Isotope labeling of amino acid has been used to study host-cell function, survival, the precise intracellular pathways in protein synthesis of HIV-1 infected human monocytederived macrophages. Identification of viral proteins from coronavirus infectious bronchitis-infected cells has been achieved with Stable Isotope labeling in conjunction with LC-MS/MS.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Gino L Turra et al.
Microbiology spectrum, 9(2), e0080921-e0080921 (2021-09-30)
Import and oxidative folding of proteins in the mitochondrial intermembrane space differ among eukaryotic lineages. While opisthokonts such as yeast rely on the receptor and oxidoreductase Mia40 in combination with the Mia40:cytochrome c oxidoreductase Erv, kinetoplastid parasites and other Excavata/Discoba
Edward Emmott et al.
Molecular & cellular proteomics : MCP, 9(9), 1920-1936 (2010-05-15)
Virus-host interactions involve complex interplay between viral and host factors, rendering them an ideal target for proteomic analysis. Here we detail a high throughput quantitative proteomics analysis of Vero cells infected with the coronavirus infectious bronchitis virus (IBV), a positive
Stephanie D Kraft-Terry et al.
Journal of proteome research, 10(6), 2852-2862 (2011-04-20)
Dynamic interactions between human immunodeficiency virus-1 (HIV-1) and the macrophage govern the tempo of viral dissemination and replication in its human host. HIV-1 affects macrophage phenotype, and the macrophage, in turn, can modulate the viral life cycle. While these processes

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