668486

(+)-1,2-Bis[(2S,5S)-2,5-diethylphospholano]benzene

Namena purity

• Synonym(s): (2S,2′S,5S,5′S)-2,2′,5,5′-Tetraethyl-1,1′-(o-phenylene)diphospholane, (S,S)-Ethyl-DUPHOS
• Empirical Formula (Hill Notation): C₂₂H₃₆P₂
• CAS Number: 136779-28-7
• Molecular Weight: 362.47
• Beilstein/REAXYS Number: 4814174
• MDL number: MFCD00142321
• UNSPSC Code: 12352005
• PubChem Substance ID: 24884986
• NACRES: NA.22

Properties

• Quality Level: 100
• refractive index: n20/D 1.581
• density: 1.010 g/mL at 25 °C
• functional group: phosphine
• SMILES string: CC[C@H]1CC[C@H](CC)P1c2ccccc2P3[C@@H](CC)CC[C@@H]3CC
• InChI: 1S/C22H36P2/c1-5-17-13-14-18(6-2)23(17)21-11-9-10-12-22(21)24-19(7-3)15-16-20(24)8-4/h9-12,17-20H,5-8,13-16H2,1-4H3/t17-,18-,19-,20-/m0/s1
• InChI key: GVVCHDNSTMEUCS-MUGJNUQGSA-N

Description

Application

DuPhos and BPE Ligands: Highly Efficient Privileged Ligands

(+)-1,2-Bis[(2S,5S)-2,5-diethylphospholano]benzene is a chiral ligand that can be used to prepare its rhodium metal complexes, which are used as catalysts in asymmetric hydrogenation reactions.[1][2][3][4]

Legal Information

Sold in collaboration with Namena Corp. for research purposes only. These compounds were made and sold under license from E.I. du Pont de Nemours and Company, which license does not include the right to use the compounds in producing products for sale in the pharmaceutical field.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter