668524

(+)-1,2-Bis[(2R,5R)-2,5-diisopropylphospholano]benzene

kanata purity

• Synonym(s): (R,R)-i-Pr-DUPHOS
• Empirical Formula (Hill Notation): C₂₆H₄₄P₂
• CAS Number: 136705-65-2
• Molecular Weight: 418.58
• MDL number: MFCD02684549
• PubChem Substance ID: 24884989
• NACRES: NA.22

Properties

• Quality Level: 100
• form: solid
• optical activity: [α]20/D +103°, c = 1 in chloroform
• refractive index: n20/D 1.5701
• SMILES string: CC(C)[C@H]1CC[C@H](C(C)C)P1c2ccccc2P3[C@H](CC[C@@H]3C(C)C)C(C)C
• InChI: 1S/C26H44P2/c1-17(2)21-13-14-22(18(3)4)27(21)25-11-9-10-12-26(25)28-23(19(5)6)15-16-24(28)20(7)8/h9-12,17-24H,13-16H2,1-8H3/t21-,22-,23-,24-/m1/s1
• InChI key: RBVGOQHQBUPSGX-MOUTVQLLSA-N

Description

General description

Optical rotation devation ± 13

Application

DuPhos and BPE Ligands: Highly Efficient Privileged Ligands

(R,R)-i-Pr-DUPHOS is a chiral phospholane class of ligand that can be used in:

• The catalytic asymmetric hydrogenation reactions.
• Rhodium catalyzed enantioselective synthesis of 1,2 diols via asymmetric intramolecular hydrosilylation of α- and β-hydroxyketones.
• In the enantioselective synthesis of diarylmethanols by arylation of aromatic aldehydes with arylboronic acids in the presence of a rhodium catalyst.

Legal Information

Sold in collaboration with Kanata Chemical Technologies Inc. for research purposes only. These compounds were made and sold under license from E.I. du Pont de Nemours and Company, which license does not include the right to use the compounds in producing products for sale in the pharmaceutical field.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): 230.0 °F
• Flash Point(C): > 110 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves