689440

O-(2-Azidoethyl)heptaethylene glycol

≥95% (oligomer purity)

• Synonym(s): Azido-PEG (n=7)
• Empirical Formula (Hill Notation): C₁₆H₃₃N₃O₈
• CAS Number: 352439-36-2
• Molecular Weight: 395.45
• Beilstein/REAXYS Number: 8940056
• MDL number: MFCD08274607
• UNSPSC Code: 12352200
• PubChem Substance ID: 329761266
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥95% (oligomer purity)
• form: powder
• mol wt: average M_n 400
• reaction suitability: reaction type: click chemistry; reagent type: cross-linking reagent
• Ω-end: hydroxyl
• α-end: azide
• functional group: azide; hydroxyl
• storage temp.: 2-8°C
• SMILES string: OCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
• InChI: 1S/C16H33N3O8/c17-19-18-1-3-21-5-7-23-9-11-25-13-15-27-16-14-26-12-10-24-8-6-22-4-2-20/h20H,1-16H2
• InChI key: BUMODEBRFGPXRM-UHFFFAOYSA-N

Description

Application

O-(2-Azidoethyl)heptaethylene glycol is used to synthesize oligo and poly(ethylene glycol) derivatives that are used as structural units of dendrimers, hydrogels, surface modifiers, self-assembling systems and molecular crosslinkers.[1][2][3][4][5][6] This precursor is compatible for acetylene-azide click reactions.[5]

Some of the reported applications include:

• Synthesis of strain-stiffening hydrogels through self-assembly of oligomers fibres derived from Azido-PEG (n=7).[1]
• Synthesis of biodegradable tetra-PEG hydrogels for drug delivery system.[2]
• Synthesis of heterobifunctional oligo(ethylene glycol) linkers for bioconjugation and targeted drug delivery.[3]
• Preparation of synthetic amphiphiles for programmed pH-dependent dispersions of carbon nanotubes (CNTs).[4]
• Selective glycoprotein detection through allosteric click-imprinting by using a self-assembled monolayer developed from the above oligomer.[5]
• Preparation of bioactivated quantum dot micelles containing fluorescent nanocrystals.[6]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves