Di-tert-butyl dicarbonate solution

2 M in methylene chloride

Di-tert-butyl pyrocarbonate
Linear Formula:
CAS Number:
Molecular Weight:
MDL number:
PubChem Substance ID:

Quality Level


2 M in methylene chloride


1.162 g/mL at 25 °C

SMILES string




InChI key


Looking for similar products? Visit Product Comparison Guide

Signal Word



Acute Tox. 1 Inhalation - Carc. 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1


6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK Germany


Flash Point(F)

224.6 °F

Flash Point(C)

107 °C

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Giuseppe Bartoli et al.
The Journal of organic chemistry, 71(26), 9580-9588 (2006-12-16)
The reaction between alcohols and Boc2O leads to the formation of tert-butyl ethers and/or Boc-alcohols, depending on the nature of the Lewis acid catalyst. Product distribution is mainly tuned by the anionic part of the salt. Perchlorates and triflates, anions...
Jason C Green et al.
Organic letters, 13(20), 5500-5503 (2011-09-21)
Total syntheses of two structures purported as (+)-heliananes were completed in six pots. Spectral comparisons, between the synthetic and natural compounds, revealed a misassignment of the eight-membered ring in the heliananes. The key step in the syntheses of the proposed...
Brandon S Fowler et al.
Journal of the American Chemical Society, 132(9), 2870-2871 (2010-02-18)
We report a fundamentally unique approach to the catalytic kinetic resolution of amine derivatives based on formamide and thioformamide substrates. Readily accessible histidine-containing peptides mediate the kinetic resolutions with as little as 5 mol % catalyst. Selectivity factors (k(rel)) as...
Asit K Chakraborti et al.
Organic & biomolecular chemistry, 4(14), 2769-2771 (2006-07-11)
Perchloric acid adsorbed on silica-gel (HClO4-SiO2) was found to be a new, highly efficient, inexpensive and reusable catalyst for chemoselective N-tert-butoxycarbonylation of amines at room temperature and under solvent-free conditions.
J S Allen et al.
Mutation research, 170(1-2), 23-29 (1986-04-01)
The Ames Salmonella/mammalian-microsome assay was used to evaluate the bacterial mutagenicity of 6 bioactive peptides and of 11 chemical reagents used in peptide synthesis. Samples of 2 reagents, bis(2-oxo-3-oxazolidinyl)phosphinic chloride and fluoren-9-ylmethyl chloroformate, showed mutagenic activity with strains TA100 and...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service