739626

25-Hydroxyvitamin D₃ (6,19,19-d₃) solution

5 μg/mL in ethanol, 97 atom % D, 98% (CP)

• Synonym(s): 25-Hydroxycholecalciferol (6,19,19-d₃) solution, Deuterated 25-hydroxyvitamin D₃
• Empirical Formula (Hill Notation): C₂₇D₃H₄₁O₂
• CAS Number: 140710-94-7
• Molecular Weight: 403.66
• EC Number: 200-578-6
• MDL number: MFCD11656128
• UNSPSC Code: 12352106
• PubChem Substance ID: 329765366
• NACRES: NA.24

Properties

• isotopic purity: 97 atom % D
• Quality Level: 200
• assay: 98% (CP)
• form: liquid
• concentration: 5 μg/mL in ethanol
• technique(s): mass spectrometry (MS): suitable
• color: colorless
• application(s): detection
• mass shift: M+3
• storage temp.: −20°C
• SMILES string: [2H]/C([2H])=C1CC[C@H](O)CC\1=C([2H])\C=C2/CCC[C@]3(C)[C@H](CC[C@@H]23)[C@H](C)CCCC(C)(C)O
• InChI: 1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1/i1D2,12D
• InChI key: JWUBBDSIWDLEOM-CMMPNOGOSA-N

Description

General description

25-Hydroxyvitamin D₃ (calcifediol) is a prohormone produced via hydroxylation of vitamin D₃ (cholecalciferol) in the liver. It is a precursor for the synthesis of calcitriol {1,25-dihydroxyvitamin D₃ or [1,25(OH)₂D₃]}. It is also used as a biomarker to determine the status of vitamin D in the body.[1][2]
25-Hydroxyvitamin D₃ (6,19,19-d₃) is a deuterated 25-hydroxyvitamin D₃ wherein C-6 and C-19 protons are replaced by deuterium.

Application

25-Hydroxyvitamin D₃ (6,19,19-d₃) can be used as an analytical standard for the quantitative analysis of hydroxyvitamin D₃ concentration in human serum via LC-MS.[3]

Packaging

1 mL in ampule

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H319
• pcodes: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 57.2 °F - closed cup
• flash_point_c: 14.0 °C - closed cup