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25-Hydroxyvitamin D₃ solution

Name: 25-Hydroxyvitamin D<SUB>3</SUB> solution
Brand: ALDRICH
Price: 224 USD
Availability: InStock

50 μg/mL in ethanol, 98% (CP)

Synonym(s):

25-Hydroxycholecalciferol solution

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Pack Size	SKU	Availability	Price
1 mL		Available to ship TODAYfromMiamisburg	$224.00

About This Item

Empirical Formula (Hill Notation):

C₂₇H₄₄O₂

CAS Number:

19356-17-3

Molecular Weight:

400.64

NACRES:

NA.24

PubChem Substance ID:

329765367

UNSPSC Code:

12352205

EC Number:

200-578-6

MDL number:

MFCD00867077

Assay:

98% (CP)

Form:

solution

$224.00

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Properties

Quality Level

200

assay

98% (CP)

form

solution

concentration

50 μg/mL in ethanol

technique(s)

mass spectrometry (MS): suitable

color

colorless

application(s)

detection

storage temp.

−20°C

SMILES string

C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C

InChI

1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1

InChI key

JWUBBDSIWDLEOM-DTOXIADCSA-N

Gene Information

human ... VDR(7421)

Description

General description

25-Hydroxyvitamin D₃ (calcifediol) is a prohormone produced via hydroxylation of vitamin D₃ (cholecalciferol) in the liver. It is a precursor for the synthesis of calcitriol {1,25-dihydroxyvitamin D₃ or [1,25(OH)₂D₃]}. It is also used as a biomarker to determine the status of vitamin D in the body.

Application

This product may be used as an analytical standard.

Packaging

1 mL in ampule

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1 of 1

This Item	739669	803103	739650
Sigma-Aldrich 739642 25-Hydroxyvitamin D₃ solution	Sigma-Aldrich 739669 25-Hydroxyvitamin D₃ solution	Sigma-Aldrich 803103 25-Hydroxyvitamin D3-23,24,25,26,27-¹³C₅ solution	Sigma-Aldrich 739650 25-Hydroxyvitamin D₃ solution
technique(s) mass spectrometry (MS): suitable	technique(s) mass spectrometry (MS): suitable	technique(s) mass spectrometry (MS): suitable	technique(s) mass spectrometry (MS): suitable
assay 98% (CP)	assay 98% (CP)	assay 95%	assay 98% (CP)
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
form solution	form solution	form liquid	form solution
concentration 50 μg/mL in ethanol	concentration 5 μg/mL in ethanol	concentration 100 μg/mL in ethanol	concentration 100 μg/mL in ethanol
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

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pictograms

GHS02,GHS07

signalword

Danger

hcodes

H225,H319

pcodes

P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

57.2 °F

flash_point_c

14.0 °C

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25-Hydroxyvitamin D3, the prohormone of 1, 25-dihydroxyvitamin D3, inhibits the proliferation of primary prostatic epithelial cells

Barreto, AM et al.

Cancer Epidemiology, Biomarkers & Prevention, 9(3), 265-270 (2000)

Noncompetitive immunoassay detection system for haptens on the basis of antimetatype antibodies.

Kazuya Omi et al.

Clinical chemistry, 61(4), 627-635 (2015-02-20)

Small molecules classified as haptens are generally measured by competitive immunoassay, which is theoretically inferior to noncompetitive sandwich immunoassay in terms of sensitivity and specificity. We created a method for developing sandwich immunoassays to measure haptens on the basis of

Vitamin D Status in Rheumatoid Arthritis: Inflammation, Arterial Stiffness and Circulating Progenitor Cell Number.

Alberto Lo Gullo et al.

PloS one, 10(8), e0134602-e0134602 (2015-08-05)

Suboptimal vitamin D status was recently acknowledged as an independent predictor of cardiovascular diseases and all-cause mortality in several clinical settings, and its serum levels are commonly reduced in Rheumatoid Arthritis (RA). Patients affected by RA present accelerated atherosclerosis and

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Global Trade Item Number

SKU	GTIN
739642-1ML	04061838085184

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