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739669

25-Hydroxyvitamin D3 solution

5 μg/mL in ethanol, 98% (CP)

Synonym(s):

25-Hydroxycholecalciferol solution

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1 ML

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About This Item

Empirical Formula (Hill Notation):
C27H44O2
CAS Number:
19356-17-3
Molecular Weight:
400.64
NACRES:
NA.24
PubChem Substance ID:
329765369
UNSPSC Code:
12352205
EC Number:
200-578-6
MDL number:
MFCD00867077
Assay:
98% (CP)
Form:
solution

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InChI key

JWUBBDSIWDLEOM-DTOXIADCSA-N

InChI

1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1

SMILES string

C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C

assay

98% (CP)

form

solution

concentration

5 μg/mL in ethanol

technique(s)

mass spectrometry (MS): suitable

color

colorless

application(s)

detection

storage temp.

−20°C

Quality Level

200

Gene Information

human ... VDR(7421)

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1 of 4

This Item
739642803103H4014
25-Hydroxyvitamin D3 solution 5 μg/mL in ethanol, 98% (CP)

Sigma-Aldrich

739669

25-Hydroxyvitamin D3 solution

25-Hydroxyvitamin D3 solution 50 μg/mL in ethanol, 98% (CP)

Sigma-Aldrich

739642

25-Hydroxyvitamin D3 solution

25-Hydroxyvitamin D3-23,24,25,26,27-13C5 solution 100 μg/mL in ethanol, 99 atom % 13C, 95%

Sigma-Aldrich

803103

25-Hydroxyvitamin D3-23,24,25,26,27-13C5 solution

25-Hydroxycholecalciferol ≥98% (HPLC)

Sigma-Aldrich

H4014

25-Hydroxycholecalciferol

assay

98% (CP)

assay

98% (CP)

assay

95%

assay

≥98% (HPLC)

technique(s)

mass spectrometry (MS): suitable

technique(s)

mass spectrometry (MS): suitable

technique(s)

mass spectrometry (MS): suitable

technique(s)

HPLC: suitable

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

solution

form

solution

form

liquid

form

powder

concentration

5 μg/mL in ethanol

concentration

50 μg/mL in ethanol

concentration

100 μg/mL in ethanol

concentration

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

25-Hydroxyvitamin D3 (calcifediol) is a prohormone produced via hydroxylation of vitamin D3 (cholecalciferol) in the liver. It is a precursor for the synthesis of calcitriol {1,25-dihydroxyvitamin D3 or [1,25(OH)2D3]}. It is also used as a biomarker to determine the status of vitamin D in the body.[1][2]

Application

This product may be used as an analytical standard.

Packaging

1 mL in ampule

related product

Product No.
Description
Pricing

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

hcodes

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

57.2 °F

flash_point_c

14.0 °C

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Certificates of Analysis (COA)

Lot/Batch Number
MBBF0044
MBBD6895
MBBD4820
MBBC7301
MBBC4030

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Fadia S AlBuhairan et al.
The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 57(3), 263-269 (2015-08-25)
With the increasing burden of noncommunicable disease, adolescence is viewed as an opportune time to prevent the onset of certain behaviors and promote healthy states. Although adolescents comprise a considerable portion of Saudi Arabia's population, they have received insufficient attention
Peter Daley et al.
The Lancet. Infectious diseases, 15(5), 528-534 (2015-04-13)
Vitamin D has immunomodulatory effects that might aid clearance of mycobacterial infection. We aimed to assess whether vitamin D supplementation would reduce time to sputum culture conversion in patients with active tuberculosis. We did this randomised, double-blind, placebo-controlled, superiority trial
Alberto Lo Gullo et al.
PloS one, 10(8), e0134602-e0134602 (2015-08-05)
Suboptimal vitamin D status was recently acknowledged as an independent predictor of cardiovascular diseases and all-cause mortality in several clinical settings, and its serum levels are commonly reduced in Rheumatoid Arthritis (RA). Patients affected by RA present accelerated atherosclerosis and
Marina V Antunes et al.
Therapeutic drug monitoring, 37(6), 733-744 (2015-04-09)
In view of the large variability on therapeutic response and the multiple factors associated to tamoxifen (TAM) metabolic activation, this study aimed to evaluate the effect of CYP2D6 and CYP3A4 phenotypes, drug interactions, and vitamin D exposure on TAM metabolism
Joseph Schwager et al.
Molecular nutrition & food research, 59(8), 1513-1523 (2015-03-27)
The impact of L-ascorbic acid (L-AA) on the chemokinesis (CK) and chemotaxis (CT) of HL-60 cells and polymorphonuclear cells (PMN) was investigated. HL-60 cells were differentiated with DMSO, retinoic acid (RA), vitamin D, or L-AA. Chemokinesis and chemotaxis of differentiated
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