742503

Sigma-Aldrich

Calcium silicate

purum, 12-22% Ca (as CaO) basis, ≥87% SiO2 basis

CAS Number:
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

grade

purum

assay

≥87% SiO2 basis
12-22% Ca (as CaO) basis

composition

Ca (as CaO), 12-22% T

loss

≤7.0% loss on drying, 2h; 105°C

particle size

7.0-10.0 μm

pH

9.5-11.5 (5% in H2O)

density

2.9 g/mL at 25 °C (lit.)

SMILES string

[Ca++].[O-][Si]([O-])=O

InChI

1S/Ca.O3Si/c;1-4(2)3/q+2;-2

InChI key

OYACROKNLOSFPA-UHFFFAOYSA-N

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Application

Calcium silicate can be used as a precursor to synthesize several biomaterials. Examples for such applications include the preparation of biocompatible nanocomposites for bone tissue regeneration and the synthesis of sol-gel hybrid bioactive glasses.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Rania Hassan Fahmy
AAPS PharmSciTech, 13(3), 990-1004 (2012-07-19)
Multiparticulate floating drug delivery systems have proven potential as controlled-release gastroretentive drug delivery systems that avoid the "all or none" gastric emptying nature of single-unit floating dosage forms. An objective of the presence investigation was to develop calcium silicate (CaSi)/calcium...
Emma C Goethals et al.
Langmuir : the ACS journal of surfaces and colloids, 29(2), 658-666 (2012-10-20)
Polymer nanocapsules have gained an important place as drug delivery vehicles for a myriad of biomedical applications. However, the influence of nanocapsule size, wall thickness, and porosity toward controlling the drug delivery efficiency of nanocapsular systems is not well understood....
S S Salek et al.
Applied microbiology and biotechnology, 97(6), 2743-2752 (2012-11-29)
Silicate minerals can be a source of calcium and alkalinity, enabling CO2 sequestration in the form of carbonates. For this to occur, the mineral needs to be first dissolved in an acidifying process such as the biological process of anaerobic...
Bobo Yu et al.
Langmuir : the ACS journal of surfaces and colloids, 28(50), 17465-17476 (2012-11-23)
The aim was to determine the most effective calcium precursor for synthesis of sol-gel hybrids and for improving homogeneity of sol-gel bioactive glasses. Sol-gel derived bioactive calcium silicate glasses are one of the most promising materials for bone regeneration. Inorganic/organic...
Haiyan Li et al.
Acta biomaterialia, 9(2), 5379-5389 (2012-10-24)
Angiogenesis is critical for bone tissue engineering. Stimulating proangiogenesis in an engineered bone construct using bioglass or bioceramic is now attracting much attention. However, the specific ion that plays important roles in the stimulation of proangiogenesis has not yet been...

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