749648

2-[2-(Boc-amino)ethoxy]ethanol

97%

• Synonym(s): 2-(2-tert-Butoxycarbonylaminoethoxy)ethanol, N-[2-(2-Hydroxyethoxy)ethyl]carbamic acid tert-butyl ester, tert-Butyl[2-(2-hydroxyethoxy)ethyl]carbamate, [2-(2-Hydroxyethoxy)ethyl]carbamic acid 1,1-dimethylethyl ester
• Empirical Formula (Hill Notation): C₉H₁₉NO₄
• CAS Number: 139115-91-6
• Molecular Weight: 205.25
• MDL number: MFCD04038542
• UNSPSC Code: 12352100
• PubChem Substance ID: 329766008
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 97%
• form: liquid
• refractive index: n20/D 1.454
• density: 1.061 g/mL at 25 °C
• functional group: amine; ether; hydroxyl
• SMILES string: CC(C)(C)OC(=O)NCCOCCO
• InChI: 1S/C9H19NO4/c1-9(2,3)14-8(12)10-4-6-13-7-5-11/h11H,4-7H2,1-3H3,(H,10,12)
• InChI key: KSFVNEXYCULLEJ-UHFFFAOYSA-N

Description

Application

2-[2-(Boc-amino)ethoxy]ethanol is N-terminal protected 2-(2-aminoethoxy)ethanol. It is generally used as a molecular spacer/linker. Some of such applications are:

• Synthesis of biotinylated HaloLigands to prepare quantum dot adducts for HaloTag protein-mediated specific labeling of live cells.[1]
• It is one of the key precursors for the total synthesis of tyroscherin and photo-activatable tyroscherin-based affinity reagent used for identification of tyroscherin binding proteins.[2]
• It can be used to link HaloTag enzyme with fluorescent zinc indicator, ZIMIR to monitor the dynamics of regulated secretion of zinc in real time.[3]
• It can also be used to synthesize amphiphiles for DNA and siRNA delivery.[4]

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H315,H319
• pcodes: P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable