All Photos(1)
Synonym(s):
5-Benzylmercapto-1,2,3,4-tetrazole, 5-Benzylmercaptotetrazole, 5-Benzylthio-1H-tetrazole, 5-[(Phenylmethyl)thio]-2H-tetrazole
Empirical Formula (Hill Notation):
C8H8N4S
CAS Number:
Molecular Weight:
192.24
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Quality Level
assay
≥99.0% (HPLC)
form
crystals
mp
135-138 °C (DSC-onset)
SMILES string
C(Sc1nnn[nH]1)c2ccccc2
InChI
1S/C8H8N4S/c1-2-4-7(5-3-1)6-13-8-9-11-12-10-8/h1-5H,6H2,(H,9,10,11,12)
InChI key
GXGKKIPUFAHZIZ-UHFFFAOYSA-N
Related Categories
General description
5-(Benzylthio)-1H-tetrazole (BTT activator) is an organic compound that is used as an activator in the synthesis of oligonucleotides. The activator reacts with the phosphoramidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′-hydroxyl group of the growing oligonucleotide chain.
Other Notes
Activator for DNA synthesis; superior alternative to tetrazole
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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S. Pitsch et al.
Helvetica Chimica Acta, 84, 3773-3773 (2001)
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